日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Do RND efflux pumps require protomeric cooperativity within the trimer to mediate antimicrobial resistance?

RND 外排泵是否需要三聚体内部的亚基协同作用来介导抗菌素耐药性?

Zhang, Zhemin; Klenotic, Philip A; Hung, Wei-Tse; Maharjan, Rakesh; Kundracik, Emma; Gregor, William D; Yu, Edward W

Cryo-EM structures of the small-conductance Ca(2+)-activated K(Ca)2.2 channel

小电导Ca(2+)激活K(Ca)2.2通道的冷冻电镜结构

Nam, Young-Woo; Im, Dohyun; Garcia, Ana Santa Cruz; Tringides, Marios L; Nguyen, Hai Minh; Liu, Yan; Orfali, Razan; Ramanishka, Alena; Pintilie, Grigore; Su, Chih-Chia; Cui, Meng; Logothetis, Diomedes E; Yu, Edward W; Wulff, Heike; Chandy, K George; Zhang, Miao

Structural snapshots of Pseudomonas aeruginosa LptB(2)FG and LptB(2)FGC reveal insights into lipopolysaccharide recognition and transport.

铜绿假单胞菌 LptB(2)FG 和 LptB(2)FGC 的结构快照揭示了脂多糖识别和运输的见解。

Fiorentino Francesco, Cervoni Matteo, Wang Yi, Urner Leonhard H, Sauer Joshua B, Tran Anh, Corey Robin A, Rotili Dante, Mai Antonello, Stansfeld Phillip J, Imperi Francesco, Yu Edward W, Su Chih-Chia, Robinson Carol V, Bolla Jani R

Structures of MmpL complexes reveal the assembly and mechanism of this family of transporters

MmpL复合物的结构揭示了该转运蛋白家族的组装和机制

Zhang, Zhemin; Maharjan, Rakesh; Gregor, William D; Klenotic, Philip A; Yu, Edward W

Cryo-EM structure of the Pseudomonas aeruginosa MexY multidrug efflux pump

铜绿假单胞菌 MexY 多药外排泵的冷冻电镜结构

Gregor, William D; Maharjan, Rakesh; Zhang, Zhemin; Chiaraviglio, Lucius; Sastry, Nithya; Cui, Meng; Kirby, James E; Yu, Edward W

The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.

恶性疟原虫 NCR1 转运蛋白是一种抗疟靶点,可将胆固醇从寄生虫的质膜中输出

Zhang Zhemin, Lyu Meinan, Han Xu, Bandara Sepalika, Cui Meng, Istvan Eva S, Geng Xinran, Tringides Marios L, Gregor William D, Miyagi Masaru, Oberstaller Jenna, Adams John H, Zhang Youwei, Nieman Marvin T, von Lintig Johannes, Goldberg Daniel E, Yu Edward W

Mapping Protein-Protein Interactions at Birth: Single-Particle Cryo-EM Analysis of a Ribosome-Nascent Globin Complex

绘制出生时蛋白质-蛋白质相互作用图谱:核糖体-新生珠蛋白复合物的单颗粒冷冻电镜分析

Masse, Meranda M; Hutchinson, Rachel B; Morgan, Christopher E; Allaman, Heather J; Guan, Hongqing; Yu, Edward W; Cavagnero, Silvia

Mutation-based mechanism and evolution of the potent multidrug efflux pump RE-CmeABC in Campylobacter

弯曲杆菌中强效多药外排泵 RE-CmeABC 的突变机制和进化

Dai, Lei; Wu, Zuowei; Sahin, Orhan; Zhao, Shaohua; Yu, Edward W; Zhang, Qijing

Structural analysis of resistance-nodulation cell division transporters

抗性结节细胞分裂转运体的结构分析

Klenotic, Philip A; Yu, Edward W

Cryo-EM structures of the human band 3 transporter indicate a transport mechanism involving the coupled movement of chloride and bicarbonate ions

人带3转运蛋白的冷冻电镜结构表明,其转运机制涉及氯离子和碳酸氢根离子的偶联运动。

Su, Chih-Chia; Zhang, Zhemin; Lyu, Meinan; Cui, Meng; Yu, Edward W