日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Author Correction: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice

作者更正：A152T 人类 tau 蛋白的表达会导致转基因小鼠出现与年龄相关的神经元功能障碍和丢失

期刊:EMBO Reports
影响因子:6.2
doi:10.1038/s44319-024-00212-8
Maeda, Sumihiro; Djukic, Biljana; Taneja, Praveen; Yu, Gui-Qiu; Lo, Iris; Davis, Allyson; Craft, Ryan; Guo, Weikun; Wang, Xin; Kim, Daniel; Ponnusamy, Ravikumar; Gill, T Michael; Masliah, Eliezer; Mucke, Lennart
神经科学
发表日期：2024
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Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models

增加阿尔茨海默病风险的TREM2变异体导致小鼠模型中皮质突触密度异常，并促进神经网络过度兴奋。

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2023.106263
Das, Melanie; Mao, Wenjie; Voskobiynyk, Yuliya; Necula, Deanna; Lew, Irene; Petersen, Cathrine; Zahn, Allie; Yu, Gui-Qiu; Yu, Xinxing; Smith, Nicholas; Sayed, Faten A; Gan, Li; Paz, Jeanne T; Mucke, Lennart
阿尔茨海默症
神经科学
TREM2
发表日期：2023
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Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony

Tau 减少对兴奋性和抑制性神经元的影响不同，降低兴奋/抑制比，并抵消网络超同步

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2021.109855
Che-Wei Chang, Mark D Evans, Xinxing Yu, Gui-Qiu Yu, Lennart Mucke
神经
发表日期：2021
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A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease

在阿尔茨海默病小鼠模型中，第二个X染色体有助于增强抵抗力。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aaz5677
Davis, Emily J; Broestl, Lauren; Abdulai-Saiku, Samira; Worden, Kurtresha; Bonham, Luke W; Miñones-Moyano, Elena; Moreno, Arturo J; Wang, Dan; Chang, Kevin; Williams, Gina; Garay, Bayardo I; Lobach, Iryna; Devidze, Nino; Kim, Daniel; Anderson-Bergman, Cliff; Yu, Gui-Qiu; White, Charles C; Harris, Julie A; Miller, Bruce L; Bennett, David A; Arnold, Arthur P; De Jager, Phil L; Palop, Jorge J; Panning, Barbara; Yokoyama, Jennifer S; Mucke, Lennart; Dubal, Dena B
阿尔茨海默症
发表日期：2020
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.

GluN2A NMDA 受体增强可改善 Dravet 综合征和阿尔茨海默病模型中的脑振荡、同步性和认知功能

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2019.12.030
Hanson Jesse E, Ma Keran, Elstrott Justin, Weber Martin, Saillet Sandrine, Khan Abdullah S, Simms Jeffrey, Liu Benjamin, Kim Thomas A, Yu Gui-Qiu, Chen Yelin, Wang Tzu-Ming, Jiang Zhiyu, Liederer Bianca M, Deshmukh Gauri, Solanoy Hilda, Chan Connie, Sellers Benjamin D, Volgraf Matthew, Schwarz Jacob B, Hackos David H, Weimer Robby M, Sheng Morgan, Gill T Michael, Scearce-Levie Kimberly, Palop Jorge J
神经科学
发表日期：2020
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Life extension factor klotho enhances cognition

寿命延长因子Klotho增强认知能力

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2014.03.076
Dubal, Dena B; Yokoyama, Jennifer S; Zhu, Lei; Broestl, Lauren; Worden, Kurtresha; Wang, Dan; Sturm, Virginia E; Kim, Daniel; Klein, Eric; Yu, Gui-Qiu; Ho, Kaitlyn; Eilertson, Kirsten E; Yu, Lei; Kuro-o, Makoto; De Jager, Philip L; Coppola, Giovanni; Small, Gary W; Bennett, David A; Kramer, Joel H; Abraham, Carmela R; Miller, Bruce L; Mucke, Lennart
神经科学
发表日期：2014
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Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.

左乙拉西坦可抑制神经元网络功能障碍，并逆转阿尔茨海默病模型中的突触和认知缺陷

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1121081109
Sanchez Pascal E, Zhu Lei, Verret Laure, Vossel Keith A, Orr Anna G, Cirrito John R, Devidze Nino, Ho Kaitlyn, Yu Gui-Qiu, Palop Jorge J, Mucke Lennart
神经科学
发表日期：2012
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Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits

小鼠内嗅皮层-海马网络中人类P301L突变tau蛋白的表达会导致tau蛋白聚集和突触前病变，但不会引起认知缺陷。

期刊:PLoS One
影响因子:
doi:10.1371/journal.pone.0045881
Harris, Julie A; Koyama, Akihiko; Maeda, Sumihiro; Ho, Kaitlyn; Devidze, Nino; Dubal, Dena B; Yu, Gui-Qiu; Masliah, Eliezer; Mucke, Lennart
Human
神经科学
发表日期：2012
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Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice

转基因小鼠中载脂蛋白E4的细胞来源决定了神经元对兴奋性毒性损伤的易感性

期刊:American Journal of Pathology
影响因子:3.6
doi:10.2353/ajpath.2010.090973
Buttini, Manuel; Masliah, Eliezer; Yu, Gui-Qiu; Palop, Jorge J; Chang, Shengjun; Bernardo, Aubrey; Lin, Carol; Wyss-Coray, Tony; Huang, Yadong; Mucke, Lennart
毒理研究
细胞生物学
神经科学
发表日期：2010
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Collagen VI protects neurons against Abeta toxicity

胶原蛋白VI可保护神经元免受Aβ毒性侵害

期刊:Nature Neuroscience
影响因子:20
doi:10.1038/nn.2240
Cheng, Jason S; Dubal, Dena B; Kim, Daniel H; Legleiter, Justin; Cheng, Irene H; Yu, Gui-Qiu; Tesseur, Ina; Wyss-Coray, Tony; Bonaldo, Paolo; Mucke, Lennart
毒理研究
神经科学
发表日期：2009
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