EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors
EVOLVE平台是一种三特异性T细胞衔接器，整合了CD2共刺激信号，用于治疗实体瘤和血液肿瘤。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2510829122
Sergeeva, Oksana A; Jin, Guixian; Sarkar, Mohosin; Zeiger, Jennifer; Dhindwal, Sonali; Chin, Shu Shien; Abulizi, Abudukadier; Lai, Zengzu; Brown, Colleen; DeMaria, William G; Ryan, Donal; An, Xingyue; Karp, Hayden J; Teran, Evelyn; Yuan, Changqing; Klaskin, Danielle; Reeve, Tracy A; Yu, Guoying Karen; Tam, Eric M; Kaech, Susan M; Preyer, Martin; Matis, Louis; Fine, Jay S; Martomo, Stella A; Myers, Jeremy S
肿瘤
T细胞
肿瘤免疫
信号转导
T细胞
细胞生物学
CD2
免疫/内分泌
