日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FLT201, a novel liver-directed AAV gene therapy candidate for Gaucher disease type 1.

FLT201 是一种新型的肝脏靶向 AAV 基因治疗候选药物,用于治疗 1 型戈谢病。

Comper Fabrizio, Miranda Carlos J, Liou Benjamin, Dodev Tihomir, Jeyakumar Jey M, Canavese Miriam, Cocita Clement, Khoshrou Khashayar, Tiscornia Gustavo, Chisari Elisa, Stotter Emmaline, Shehu Erald, Sridharan Sudharsan, Yu I-Mei, Pandya Jalpa, Khinder Jaminder, Northcott Natalie, Kalcheva Petya, Correia Samantha, Sun Ying, Dane Allison P, Sheridan Rose, Nathwani Amit C, Corbau Romuald

Differences in wild-type- and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies

野生型和R338L突变型凝血酶原酶复合物形成差异是R338L突变型凝血因子IX检测结果不一致的根本原因。

Foley, Jonathan H; Shehu, Erald; Riddell, Anne; Gray, Elaine; Goodale, Andrew; Yu, I-Mei; Verhoef, Daniël; Little, John; Shattock, Diane; Kitchen, Steve; Chowdary, Pratima; Corbau, Romuald; Nathwani, Amit C

Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1

SNARE 与多亚基连接复合物 Dsl1 结合的结构基础

Travis, Sophie M; DAmico, Kevin; Yu, I-Mei; McMahon, Conor; Hamid, Safraz; Ramirez-Arellano, Gabriel; Jeffrey, Philip D; Hughson, Frederick M

Myosin 7 and its adaptors link cadherins to actin.

肌球蛋白 7 及其衔接蛋白将钙黏蛋白连接到肌动蛋白

Yu I-Mei, Planelles-Herrero Vicente J, Sourigues Yannick, Moussaoui Dihia, Sirkia Helena, Kikuti Carlos, Stroebel David, Titus Margaret A, Houdusse Anne

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

运输驱动蛋白中微管刺激的ADP释放、ATP结合和力产生的保守机制

Atherton, Joseph; Farabella, Irene; Yu, I-Mei; Rosenfeld, Steven S; Houdusse, Anne; Topf, Maya; Moores, Carolyn A

Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- and arteriviridae

严重急性呼吸综合征(SARS)冠状病毒核衣壳蛋白二聚化结构域的晶体结构揭示了冠状病毒科和动脉炎病毒科之间的进化联系

Yu, I-Mei; Oldham, Michael L; Zhang, Jingqiang; Chen, Jue

Recombinant severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein forms a dimer through its C-terminal domain

重组严重急性呼吸综合征(SARS)冠状病毒核衣壳蛋白通过其C端结构域形成二聚体。

Yu, I-Mei; Gustafson, Christin L T; Diao, Jianbo; Burgner, John W 2nd; Li, Zhihong; Zhang, Jingqiang; Chen, Jue