文献库，生知库 | 链接生命科学的每一步

Integrating Molecular Analysis and the Pharmacology Network to Discover the Antioxidative Effects of Zanthoxylum piperitum Fruits

整合分子分析和药理学网络以发现花椒果实的抗氧化作用

Le, Ducdat; Dang, Thinhulinh; Dinh, Thientam; Yu, Soojung; Truong, Vinhquang; Kim, Minhee; Lyu, Su-Yun; Ahn, Kwang Seok; Lee, Mina

发表日期：2026

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Phenolics from Ilex rotunda Possess Antioxidative Effects and Block Activation of MAPK and NF-ÎºB Signaling by Inhibiting IL-2 Production in CD3/CD28 Activated Jurkat T Cells.

冬青酚类物质具有抗氧化作用，可通过抑制 CD3/CD28 活化的 Jurkat T 细胞中 IL-2 的产生来阻断 MAPK 和 NF-κB 信号的激活

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox14030281

Le Ducdat, Truong Vinhquang, Dang Thinhulinh, Yu Soojung, Dinh Thientam, Lee Mina

Integrative Discovery Through Network Pharmacology and Molecular Docking Approaches of Phenolic Compounds Isolated from Torreya nucifera to Treat Rheumatoid Arthritis

利用网络药理学和分子对接方法对从榧树中分离的酚类化合物进行整合发现，以治疗类风湿性关节炎

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms262311629

Le, Duc Dat; Dang, Thinhulinh; Truong, Vinhquang; Yu, Soojung; Yang, Seung-Hwa; Choi, Moon-Hee; Lee, Mina

关节炎

发表日期：2025

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Chemical Constituents from Osmanthus fragrans var. aurantiacus Makino with Their In Vitro and In Silico Studies Target Anti-Inflammation by Suppressing ERK 1/2 MAPK Signaling

桂花（Osmanthus fragrans var. aurantiacus Makino）的化学成分及其体外和计算机模拟研究表明，其通过抑制ERK 1/2 MAPK信号通路发挥抗炎作用

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26178421

Le, Ducdat; Dang, Thinhulinh; Truong, Vinhquang; Dinh, Thientam; Yu, Soojung; Lee, Seok-Geun; Lee, Mina

信号转导

Immunology/Inflammation

MAPK/ERK

发表日期：2025

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Bioactivities of Quinic Acids from Vitex rotundifolia Obtained by Supercritical Fluid Extraction

超临界流体萃取法从圆叶牡荆中分离得到的奎宁酸的生物活性

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox13101235

Le, Duc Dat; Jang, Young Su; Truong, Vinhquang; Yu, Soojung; Dinh, Thientam; Lee, Mina

发表日期：2024

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Anti-Inflammatory Effects and Metabolomic Analysis of Ilex Rotunda Extracted by Supercritical Fluid Extraction

超临界流体萃取法提取冬青提取物的抗炎作用及代谢组学分析

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms252211965

Le, Duc Dat; Jang, Young Su; Truong, Vinhquang; Dinh, Thientam; Dang, Thinhulinh; Yu, Soojung; Lee, Mina

代谢

发表日期：2024

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Molecular Networking and Bioassay-Guided Preparation and Separation of Active Extract and Constituents from Vicia tenuifolia Roth

利用分子网络和生物活性导向技术制备和分离细叶野豌豆（Vicia tenuifolia Roth）的活性提取物及其成分

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox12101876

Le, Duc Dat; Yu, Soojung; Dang, Thinhulinh; Lee, Mina

发表日期：2023

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Comparison of Behavior-Related Features in the MMSE Sentence in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease

行为变异型额颞叶痴呆和阿尔茨海默病患者简易精神状态检查量表句子中行为相关特征的比较

期刊:Frontiers in Aging Neuroscience

影响因子:4.5

doi:10.3389/fnagi.2021.733153

Ruiz-Garcia, Ramiro; Yu, Soojung; Richardson, Lauryn; Roberts, Angela; Pasternak, Stephen; Stewart, Chloe; Finger, Elizabeth

阿尔茨海默症

发表日期：2021

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Identification of Metabolites and Antioxidant Constituents from Pyrus ussuriensis

从乌苏里梨（Pyrus ussuriensis）中鉴定代谢物和抗氧化成分

Integrating Molecular Analysis and the Pharmacology Network to Discover the Antioxidative Effects of Zanthoxylum piperitum Fruits

整合分子分析和药理学网络以发现花椒果实的抗氧化作用

Phenolics from Ilex rotunda Possess Antioxidative Effects and Block Activation of MAPK and NF-ÎºB Signaling by Inhibiting IL-2 Production in CD3/CD28 Activated Jurkat T Cells.

冬青酚类物质具有抗氧化作用，可通过抑制 CD3/CD28 活化的 Jurkat T 细胞中 IL-2 的产生来阻断 MAPK 和 NF-κB 信号的激活

Integrative Discovery Through Network Pharmacology and Molecular Docking Approaches of Phenolic Compounds Isolated from Torreya nucifera to Treat Rheumatoid Arthritis

利用网络药理学和分子对接方法对从榧树中分离的酚类化合物进行整合发现，以治疗类风湿性关节炎

Chemical Constituents from Osmanthus fragrans var. aurantiacus Makino with Their In Vitro and In Silico Studies Target Anti-Inflammation by Suppressing ERK 1/2 MAPK Signaling

桂花（Osmanthus fragrans var. aurantiacus Makino）的化学成分及其体外和计算机模拟研究表明，其通过抑制ERK 1/2 MAPK信号通路发挥抗炎作用

Bioactivities of Quinic Acids from Vitex rotundifolia Obtained by Supercritical Fluid Extraction

超临界流体萃取法从圆叶牡荆中分离得到的奎宁酸的生物活性

Anti-Inflammatory Effects and Metabolomic Analysis of Ilex Rotunda Extracted by Supercritical Fluid Extraction

超临界流体萃取法提取冬青提取物的抗炎作用及代谢组学分析

Molecular Networking and Bioassay-Guided Preparation and Separation of Active Extract and Constituents from Vicia tenuifolia Roth

利用分子网络和生物活性导向技术制备和分离细叶野豌豆（Vicia tenuifolia Roth）的活性提取物及其成分

Comparison of Behavior-Related Features in the MMSE Sentence in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease

行为变异型额颞叶痴呆和阿尔茨海默病患者简易精神状态检查量表句子中行为相关特征的比较