日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Improvement of Catalytic Activity and Thermostability of Alginate Lyase VxAly7B-CM via Rational Computational Design Strategies

通过合理的计算设计策略提高藻酸裂解酶VxAly7B-CM的催化活性和热稳定性

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md23050198
Ma, Xin; Zhu, Ke; Wang, Kaiyang; Liao, Wenhui; Yang, Xiaohan; Yu, Wengong; Wang, Weishan; Han, Feng
发表日期：2025
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The mediator subunit complex protein MED15 promotes lipid deposition and cancer progression during hypoxia.

介导亚基复合物蛋白 MED15 在缺氧条件下促进脂质沉积和癌症进展

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.108296
Zhang Boqi, Zhu Yu, Tang Yanfei, Liu Lu, Liu Yunzhang, Li Yun, Yu Wengong, Lu Ling
肿瘤
肿瘤免疫
发表日期：2025
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The hydrophobic cluster on the surface of protein is the key structural basis for the SDS-resistance of chondroitinase VhChlABC

蛋白质表面的疏水簇是软骨素酶VhChlABC耐受SDS的关键结构基础。

期刊:Marine Life Science & Technology
影响因子:5.3
doi:10.1007/s42995-023-00201-1
Su, Juanjuan; Wu, Hao; Yin, Chengying; Zhang, Fengchao; Han, Feng; Yu, Wengong
发表日期：2024
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A "Pro-Asp-Thr" Amino Acid Repeat from Vibrio sp. QY108 Alginate Lyase Exhibits Alginate-Binding Capacity and Enhanced Soluble Expression and Thermostability

来自弧菌属 QY108 藻酸裂解酶的“Pro-Asp-Thr”氨基酸重复序列表现出藻酸结合能力，并增强了其可溶性表达和热稳定性。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25115801
Fu, Zheng; Zhang, Fengchao; Wang, Hainan; Tang, Luyao; Yu, Wengong; Han, Feng
发表日期：2024
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Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine

发现吡咯-吡啶咪唑衍生物作为新型 SIRT6 抑制剂，可增强胰腺癌对吉西他滨的敏感性

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-023-06018-1
Nannan Song #, Xian Guan #, Siqi Zhang, Yanqing Wang, Xuekai Wang, Zhongxia Lu, Daochen Chong, Jennifer Yiyang Wang, Rilei Yu, Wengong Yu, Tao Jiang, Yuchao Gu
代谢
肿瘤
胰腺癌
WB
发表日期：2023
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Citrinin Is a Potential Quorum Sensing Inhibitor against Pseudomonas aeruginosa

桔霉素是一种潜在的抗铜绿假单胞菌群体感应抑制剂

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md21050296
Ji, Hongrui; Zhao, Lu; Lv, Kaiwen; Zhang, Yuzhu; Gao, Haibo; Gong, Qianhong; Yu, Wengong
微生物学
发表日期：2023
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Biochemical Properties of a New Polysaccharide Lyase Family 25 Ulvan Lyase TsUly25B from Marine Bacterium Thalassomonas sp. LD5

来自海洋细菌 Thalassomonas sp. LD5 的新型多糖裂解酶家族 25 Ulvan 裂解酶 TsUly25B 的生化特性

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md20030168
Wang, Danni; Li, Yujiao; Han, Lu; Yin, Chengying; Fu, Yongqing; Zhang, Qi; Zhao, Xia; Li, Guoyun; Han, Feng; Yu, Wengong
微生物学
发表日期：2022
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Identification and Characterization of a New Cold-Adapted and Alkaline Alginate Lyase TsAly7A from Thalassomonas sp. LD5 Produces Alginate Oligosaccharides with High Degree of Polymerization

从海藻单胞菌LD5中鉴定和表征了一种新的耐冷碱性海藻酸裂解酶TsAly7A，该酶能产生高聚合度的海藻酸寡糖。

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md21010006
Yin, Chengying; Sun, Jiaxia; Wang, Hainan; Yu, Wengong; Han, Feng
发表日期：2022
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Effects of Module Truncation of a New Alginate Lyase VxAly7C from Marine Vibrio xiamenensis QY104 on Biochemical Characteristics and Product Distribution

海洋弧菌厦门QY104来源的新型藻酸裂解酶VxAly7C的模块截短对生化特性和产物分布的影响

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23094795
Tang, Luyao; Bao, Mengmeng; Wang, Ying; Fu, Zheng; Han, Feng; Yu, Wengong
发表日期：2022
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YsHyl8A, an Alkalophilic Cold-Adapted Glycosaminoglycan Lyase Cloned from Pathogenic Yersinia sp. 298

从致病性耶尔森氏菌298株中克隆出的嗜碱性冷适应性糖胺聚糖裂解酶YsHyl8A

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27092897
Zhang, Shilong; Li, Yujiao; Han, Feng; Yu, Wengong
发表日期：2022
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