文献库，生知库 | 链接生命科学的每一步

Newman Hunter, Shih Yu-Ru V, Hoque Jiaul, Zeng Yuze, Natesh Naveen R, Gonzales Gavin, Guo Wendi, Puviindran Vijitha, Wu Colleen, Alman Benjamin A, Varghese Shyni

信号转导

骨折

发表日期：2025

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Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing

多功能小分子缓解骨折疼痛并促进骨愈合

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202303567

Shih, Yu-Ru V; Kingsley, David; Newman, Hunter; Hoque, Jiaul; Gupta, Ankita; Lascelles, B Duncan X; Varghese, Shyni

骨折

发表日期：2023

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pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss

pH敏感纳米载体辅助输送腺苷治疗骨质疏松性骨质流失

期刊:Biomaterials Science

影响因子:5.8

doi:10.1039/d2bm00843b

Hunter Newman, Jiaul Hoque, Yu-Ru V Shih, Gabrielle Marushack, Unghyeon Ko, Gavin Gonzales, Shyni Varghese

Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss

骨靶向纳米载体辅助输送腺苷以对抗骨质疏松性骨质流失

期刊:Biomaterials

影响因子:12.8

doi:10.1016/j.biomaterials.2021.120819

Jiaul Hoque, Yu-Ru V Shih, Yuze Zeng, Hunter Newman, Nivedita Sangaj, Neha Arjunji, Shyni Varghese

In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing

体内螯合天然小分子以促进骨愈合

期刊:Advanced Materials

影响因子:26.8

doi:10.1002/adma.201906022

Zeng, Yuze; Shih, Yu-Ru V; Baht, Gurpreet S; Varghese, Shyni

发表日期：2020

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Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss

绝经后骨丢失期间胞外核苷酸酶介导的细胞外腺苷失调

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.aax1387

Yu-Ru V Shih ，Mengqian Liu ，Seong Keun Kwon ，Masayuki Iida ，Ya Gong ，Nivedita Sangaj ，Shyni Varghese

细胞生物学

发表日期：2019

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In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation

通过 AAV-CRISPR-Cas9 介导的靶向基因调控进行原位基因治疗

期刊:Molecular Therapy

影响因子:12.1

doi:10.1016/j.ymthe.2018.04.017

Ana M Moreno, Xin Fu, Jie Zhu, Dhruva Katrekar, Yu-Ru V Shih, John Marlett, Jessica Cabotaje, Jasmine Tat, John Naughton, Leszek Lisowski, Shyni Varghese, Kang Zhang, Prashant Mali

信号转导

发表日期：2018

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Mineralized Biomaterials Mediated Repair of Bone Defects Through Endogenous Cells

矿化生物材料通过内源性细胞介导骨缺损修复

期刊:Tissue Engineering Part A

影响因子:3.5

doi:10.1089/ten.TEA.2017.0297

Eva C González Díaz, Yu-Ru V Shih, Manando Nakasaki, Mengqian Liu, Shyni Varghese

Direct Conversion of Human Pluripotent Stem Cells to Osteoblasts With a Small Molecule

利用小分子将人类多能干细胞直接转化为成骨细胞

期刊:Current Protocols in Stem Cell Biology

影响因子:

doi:10.1002/cpsc.44

Heemin Kang, Yu-Ru V Shih, Shyni Varghese

Specialized pro-resolving mediator Maresin 1 attenuates pain in a mouse model of osteoarthritis

特异性促消退介质 Maresin 1 可减轻小鼠骨关节炎模型中的疼痛

Enabling adenosine signaling to promote aged fracture healing.

激活腺苷信号传导以促进老年骨折愈合

Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing

多功能小分子缓解骨折疼痛并促进骨愈合

pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss

pH敏感纳米载体辅助输送腺苷治疗骨质疏松性骨质流失

Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss

骨靶向纳米载体辅助输送腺苷以对抗骨质疏松性骨质流失

In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing

体内螯合天然小分子以促进骨愈合

Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss

绝经后骨丢失期间胞外核苷酸酶介导的细胞外腺苷失调

In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation

通过 AAV-CRISPR-Cas9 介导的靶向基因调控进行原位基因治疗

Mineralized Biomaterials Mediated Repair of Bone Defects Through Endogenous Cells

矿化生物材料通过内源性细胞介导骨缺损修复

Direct Conversion of Human Pluripotent Stem Cells to Osteoblasts With a Small Molecule

利用小分子将人类多能干细胞直接转化为成骨细胞