Yu-Sheng Cong相关文献与解析，生知库 | 链接生命科学的每一步

Dysregulation of PD-L1 by UFMylation imparts tumor immune evasion and identified as a potential therapeutic target

UFMylation 导致 PD-L1 失调，导致肿瘤免疫逃避，并被确定为潜在的治疗靶点

期刊:Proceedings of the National Academy of Sciences of the United States of America

Junzhi Zhou, Xiaohe Ma, Xingrui He, Beiying Chen, Jiao Yuan, Zhemin Jin, Lijing Li, Zhiguo Wang, Qian Xiao, Yafei Cai, Yongkang Zou, Yu-Sheng Cong

TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment

TERT 激活内源性逆转录病毒，促进免疫抑制肿瘤微环境

期刊:EMBO Reports

影响因子:6.5

doi:10.15252/embr.202152984

Jian Mao #, Qian Zhang #, Yaxiang Wang, Yang Zhuang, Lu Xu, Xiaohe Ma, Di Guan, Junzhi Zhou, Jiang Liu, Xiaoying Wu, Qian Liang, Miao Wang, Yu-Sheng Cong

Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1

Ufl1 缺乏通过上调内皮素-1 导致皮肤色素沉着

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.6

doi:10.3389/fcell.2022.961675

Ke Wang, Hu-Ning Xu, Yi-Wen Wang, Jian Mao, Da Liu, Xiao-Jing Zhu, Yu-Sheng Cong, Miao Wang

Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease

从上游近同源起始密码子翻译而来的人类 UFSP1 可作为活性 UFM1 特异性蛋白酶发挥作用

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2022.102016

Qian Liang, Yaqi Jin, Shiwen Xu, Junzhi Zhou, Jian Mao, Xiaohe Ma, Miao Wang, Yu-Sheng Cong

Optimized protocol to detect protein UFMylation in cells and in vitro via immunoblotting

通过免疫印迹法检测细胞和体外蛋白质 UFMylation 的优化方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2021.101074

Junzhi Zhou, Qian Liang, Maogong Dong, Xiaohe Ma, Yaqi Jin, Di Guan, Jiang Liu, Miao Wang, Yu-Sheng Cong

UFMylation maintains tumour suppressor p53 stability by antagonizing its ubiquitination

UFMylation 通过拮抗其泛素化来维持肿瘤抑制因子 p53 的稳定性

期刊:Nature Cell Biology

影响因子:17.3

doi:10.1038/s41556-020-0559-z

Jiang Liu #, Di Guan #, Maogong Dong, Jingjing Yang, Haibin Wei, Qian Liang, Lizhi Song, Lu Xu, Junjie Bai, Cui Liu, Jian Mao, Qian Zhang, Junzhi Zhou, Xiaoying Wu, Miao Wang, Yu-Sheng Cong

肿瘤

发表日期：2020

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Human telomerase reverse transcriptase is a novel target of Hippo-YAP pathway

人类端粒酶逆转录酶是 Hippo-YAP 通路的新靶点

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.201902147R

Qian Zhang, Ning Liu, Junjie Bai, Qi Zhou, Jian Mao, Lu Xu, Jiang Liu, Haibin Wei, Chengcheng Ren, Xiaoying Wu, Miao Wang, Bin Zhao, Yu-Sheng Cong

MRE11 UFMylation promotes ATM activation

MRE11 UFMylation 促进 ATM 激活

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkz110

Zhifeng Wang, Yamin Gong, Bin Peng, Ruifeng Shi, Dan Fan, Hongchang Zhao, Min Zhu, Haoxing Zhang, Zhenkun Lou, Jianwei Zhou, Wei-Guo Zhu, Yu-Sheng Cong, Xingzhi Xu

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

DDRGK1 通过调节 IRE1α 的稳定性在内质网稳态中发挥关键作用

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms14186

Jiang Liu, Ying Wang, Lizhi Song, Linghua Zeng, Weiwei Yi, Ting Liu, Huanzhen Chen, Miao Wang, Zhenyu Ju, Yu-Sheng Cong

UFMylation of HRD1 regulates endoplasmic reticulum homeostasis

HRD1 的 UFMylation 调节内质网稳态

Dysregulation of PD-L1 by UFMylation imparts tumor immune evasion and identified as a potential therapeutic target

UFMylation 导致 PD-L1 失调，导致肿瘤免疫逃避，并被确定为潜在的治疗靶点

TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment

TERT 激活内源性逆转录病毒，促进免疫抑制肿瘤微环境

Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1

Ufl1 缺乏通过上调内皮素-1 导致皮肤色素沉着

Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease

从上游近同源起始密码子翻译而来的人类 UFSP1 可作为活性 UFM1 特异性蛋白酶发挥作用

Optimized protocol to detect protein UFMylation in cells and in vitro via immunoblotting

通过免疫印迹法检测细胞和体外蛋白质 UFMylation 的优化方案

UFMylation maintains tumour suppressor p53 stability by antagonizing its ubiquitination

UFMylation 通过拮抗其泛素化来维持肿瘤抑制因子 p53 的稳定性

Human telomerase reverse transcriptase is a novel target of Hippo-YAP pathway

人类端粒酶逆转录酶是 Hippo-YAP 通路的新靶点

MRE11 UFMylation promotes ATM activation

MRE11 UFMylation 促进 ATM 激活

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

DDRGK1 通过调节 IRE1α 的稳定性在内质网稳态中发挥关键作用