日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Short-chain acyl-CoA dehydrogenase initiates mtDNA demethylation and leakage to fuel antitumor immunity in colorectal cancer.

短链酰基辅酶A脱氢酶启动线粒体DNA去甲基化和泄漏，从而促进结直肠癌的抗肿瘤免疫。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02675-8
Yang Fang, Wang Meng, Hu Shaofan, Guan Xu, Zhao Kun, Zhou Yong, Yao Hui, Zhang Tianying, Li Liuli, Gao Yuan, Zhao Sijie, Liu Nan, Xiao Weidong, Xiang Yuancai, Miao Hongming
肠癌
表观遗传
肿瘤免疫
线粒体
发表日期：2026
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Facet-modulated ferroelectric polymers

面调制铁电聚合物

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68855-w
Cai, Bo; Hou, Zhi-Ling; Qi, Yuan-Yuan; Zhao, Pei-Yan; Peng, Hua-Long; Zhang, Yu; Koo, Martin C; Yue, Tongcai; Hu, Pengfei; Liu, Li-Min; Wang, Guang-Sheng
发表日期：2026
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Gut microbiota drives the metabolic dysregulation in obesity-prone individuals by impairing GDCA-mediated activation of brown adipose thermogenesis and ileal GLP-1 secretion

肠道菌群通过损害GDCA介导的棕色脂肪组织产热和回肠GLP-1分泌，驱动肥胖易感人群的代谢紊乱。

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.12.006
Ma, Han; Wu, Yuqi; Li, Delong; Sun, Haowen; Xie, Yuan; Zhao, Shichun; Guo, Wenqian; Wang, Meng; Cui, Renyun; Huang, Yanrong; Zhang, Xiankang; Wan, Jin-Yi; Yao, Haiqiang; Yuan, Chun-Su
GLP-1
代谢
微生物学
肠道菌群
肥胖
发表日期：2026
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The castration-resistant prostate cancer-associated SNP rs11067228 facilitates neuroendocrine differentiation through an enhancer-mediated chromatin interaction with SRRM4.

与去势抵抗性前列腺癌相关的 SNP rs11067228 通过增强子介导的染色质与 SRRM4 的相互作用促进神经内分泌分化。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.124731
Jiang Yuan, Zhao Zhenhao, Li Peng, Su Guangsong, Qian Yuyang, Zhao Yuting, Wang Bo, Bai Yunlong, Zhang Lei, Zhao Zhongfang, Shi Jiandang, Lu Wange
前列腺癌
神经科学
发表日期：2026
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The Crohn's disease-related RNF123 prevents NLRP3 inflammasome assembly by catalyzing unanchored K63-linked ubiquitination on NEK7

与克罗恩病相关的RNF123通过催化NEK7上非锚定K63连接的泛素化来阻止NLRP3炎症小体的组装。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2518759123
Liu, Feng; Zhuang, Wanxin; Yang, Yuan; Zhao, Wenting; Li, Siyuan; Zhang, Ziyue; Liu, Yifan; Liu, Bingyu; Qi, Xiaopeng; Zhao, Wei; Da, Lintai; Gao, Chengjiang
炎性小体
发表日期：2026
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Krüppel-like factor 15 ameliorates alcohol-induced liver injury in mice via regulation of the PFKFB3/AKT axis.

Krüppel 样因子 15 通过调节 PFKFB3/AKT 轴来改善小鼠酒精性肝损伤。

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01651-2
Chen Hao, Yang Lin, Li Xiao-Feng, Han Si-Yuan, Zhao Qi, Xiao Rong-Cheng, Ou Zi-Yao, Fang Ling, Du Yan
AKT
肝损伤
毒理研究
PFKFB3
发表日期：2026
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Polysaccharides reinforced sesame oil body interface as 3D printing inks for dysphagia food: focusing on structural characteristics and rheological properties

多糖增强芝麻油本体界面作为3D打印墨水用于吞咽困难食品：重点研究其结构特征和流变性能

期刊:Food Chemistry-X
影响因子:8.2
doi:10.1016/j.fochx.2026.103711
Yang, Yanan; Yang, Ruizhi; Wang, Wentao; Fang, Yuan; Zhao, Luping
3D/类器官
发表日期：2026
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The application of pre-trained large visual-language models for preliminary diagnosis of esophageal whitish plaques in large-scale esophageal cancer screening

预训练大型视觉语言模型在食管癌大规模筛查中对食管白色斑块进行初步诊断的应用

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-026-01301-8
Li, Yilin; Li, Xin; Zhang, Di; Zhu, Wenwen; Hu, Yuan; Zhao, Zijian; Zhao, Qi
食管癌
肿瘤
肿瘤免疫
发表日期：2026
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Anthocyanin Derived NIR Fluorogenic Probe for Direct Visualization and Monitoring of DNA G‑Quadruplex in Breast Cancer Tumor Models

花青素衍生的近红外荧光探针用于直接可视化和监测乳腺癌肿瘤模型中的DNA G-四链体

期刊:Chemical & Biomedical Imaging
影响因子:5.7
doi:10.1021/cbmi.5c00155
Zhang, Yuan; Zhao, Lingyun; Zheng, Yuxiang; Yu, Jiaxin; Li, Zili; Liu, Mengqin; Chen, Wen
肿瘤
乳腺癌
肿瘤免疫
IF
发表日期：2026
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Sex-Based Differences in Patients Undergoing Transcatheter Tricuspid Valve Replacement

经导管三尖瓣置换术患者的性别差异

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.125.045655
Zhang, Yi; Xiong, Tianyuan; Feng, Yuan; Zhao, Zhengang; Wei, Xin; Li, Xi; Chen, Fei; Ge, Junbo; Lu, Fanglin; Chen, Mao
发表日期：2026
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