日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hybrid AI/ML-mechanistic framework enables intelligent optimization of commercial biopharmaceutical downstream processing

混合人工智能/机器学习机制框架可实现商业生物制药下游工艺的智能优化

Wang, Rong-Zhu; Liao, Yu-Xin; Wang, Teng-Long; Jing, Xiao-Yang; Yang, Guang; Wang, Hao; Xiao, Feng; Zong, Yi; Yang, Yan; Yuan, Ye; Xian, Xuan; Yao, Shan-Jing; Jin, Lei; Lin, Dong-Qiang; Kang, Yun Kenneth

AI-enabled alkaline-resistant evolution of protein to apply in mass production

人工智能赋能的耐碱性蛋白质进化技术可应用于大规模生产

Kang, Liqi; Wu, Banghao; Zhou, Bingxin; Tan, Pan; Kang, Yun Kenneth; Yan, Yongzhen; Zong, Yi; Li, Shuang; Liu, Zhuo; Hong, Liang

Correlations Between A1C and Diabetes Knowledge, Diabetes Numeracy, and Food Security in a Vulnerable Type 2 Diabetes Population

在易感2型糖尿病人群中,A1C与糖尿病知识、糖尿病计算能力和食品安全之间的相关性

Young, Clipper F; Yun, Kenneth; Kang, Edward; Shubrook, Jay H; Dugan, Joy A

Removal of a C-terminal serine residue proximal to the inter-chain disulfide bond of a human IgG1 lambda light chain mediates enhanced antibody stability and antibody dependent cell-mediated cytotoxicity

去除人IgG1λ轻链链间二硫键附近的C端丝氨酸残基可增强抗体稳定性和抗体依赖性细胞介导的细胞毒性。

Yang Shen ,Lin Zeng ,Aiping Zhu ,Tim Blanc ,Dipa Patel ,Anthony Pennello ,Amtul Bari ,Stanley Ng ,Kris Persaud ,Yun Kenneth Kang ,Paul Balderes ,David Surguladze ,Sagit Hindi ,Qinwei Zhou ,Dale L Ludwig ,Marshall Snavely

Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes

开发一种新颖、高效的细胞培养絮凝工艺,使用刺激响应性聚合物来简化抗体纯化工艺

Yun Kenneth Kang, James Hamzik, Michael Felo, Bo Qi, Julia Lee, Stanley Ng, Gregory Liebisch, Behnam Shanehsaz, Nripen Singh, Kris Persaud, Dale L Ludwig, Paul Balderes

Protection against Clostridium difficile infection with broadly neutralizing antitoxin monoclonal antibodies

使用广谱中和抗毒素单克隆抗体预防艰难梭菌感染

Andre J Marozsan, Dangshe Ma, Kirsten A Nagashima, Brian J Kennedy, Yun Kenneth Kang, Robert R Arrigale, Gerald P Donovan, Wells W Magargal, Paul J Maddon, William C Olson

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

三聚体 HIV-1 糖蛋白 gp140 免疫原和天然 HIV-1 包膜糖蛋白具有相同的封闭和开放的四级分子结构。

Harris, Audray; Borgnia, Mario J; Shi, Dan; Bartesaghi, Alberto; He, Haifeng; Pejchal, Robert; Kang, Yun Kenneth; Depetris, Rafael; Marozsan, Andre J; Sanders, Rogier W; Klasse, Per Johan; Milne, Jacqueline L S; Wilson, Ian A; Olson, William C; Moore, John P; Subramaniam, Sriram

Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1

源自 A 亚型 HIV-1 的裂解、稳定包膜三聚体的结构和免疫原性研究

Yun Kenneth Kang, Sofija Andjelic, James M Binley, Emma T Crooks, Michael Franti, Sai Prasad N Iyer, Gerald P Donovan, Antu K Dey, Ping Zhu, Kenneth H Roux, Robert J Durso, Thomas F Parsons, Paul J Maddon, John P Moore, William C Olson