ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation
ARP2/3复合物通过mTORC1和mTORC2过度激活,介导PTEN缺陷型人类神经细胞的神经病理学变化。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2523367123
Dhaliwal, Navroop K; Weng, Octavia Yifang; Tian, Ai; Aggarwal, Aditi; Ahmed, Mai; Sun, Guoria; Bhattacharya, Afrin; Choi, Wendy W Y; Nishimura, Haruka; Chakraborty, Pragnya; Dong, Xiaoxue; Wu, Yuncheng; Wilson, Michael D; Wang, Lu-Yang; Parada, Luis F; Muffat, Julien; Li, Yun
mTOR
ORC2
PTEN
ORC1
ARP2
细胞生物学