Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation
骨肉瘤细胞对蛋氨酸的依赖性逆转为对蛋氨酸的不依赖性,导致恶性程度丧失、上皮间质表型改变和组蛋白 H3 赖氨酸甲基化改变
期刊:Frontiers in Oncology
影响因子:3.5
doi:10.3389/fonc.2022.1009548
Yusuke Aoki, Qinghong Han, Yasunori Tome, Jun Yamamoto, Yutaro Kubota, Noriyuki Masaki, Koya Obara, Kazuyuki Hamada, Justin D Wang, Sachiko Inubushi, Michael Bouvet, Steven G Clarke, Kotaro Nishida, Robert M Hoffman