日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Potent Preorganized Pyrazolidine Cyclophilin D Inhibitors Prevent Mitochondrial and Organ Injury in a Mouse Pancreatitis Disease Model

强效预组织吡唑烷环孢素D抑制剂可预防小鼠胰腺炎疾病模型中的线粒体和器官损伤

Awais, Muhammad; Woodley, Christopher M; Guo, Liqun; Rogers, Michael; Kershaw, Neil; Zacharchenko, Thomas; Shore, Emma; Kattakayam, Arjun; Mukherjee, Rajarshi; Criddle, David N; Leung, Suet C; Lee, Heather; Burgess-McCann, Joshua; Luzyanin, Konstantin; Berry, Neil G; Antonyuk, Svetlana; Lian, Lu-Yun; Sutton, Robert; O'Neill, Paul M

The structural basis of the talin-KANK1 interaction that coordinates the actin and microtubule cytoskeletons at focal adhesions

talin-KANK1 相互作用的结构基础,该相互作用协调粘着斑处的肌动蛋白和微管细胞骨架

Xingchen Li, Benjamin Thomas Goult, Christoph Ballestrem, Thomas Zacharchenko

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

邻近标记识别 Rab4 和 Rab11 家族的促迁移内吞回收货物和机制

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C Norman, Thomas Zacharchenko, Patrick T Caswell

Molecular insights into titin's A-band

肌联蛋白A带的分子机制研究

Fleming, Jennifer R; Müller, Iljas; Zacharchenko, Thomas; Diederichs, Kay; Mayans, Olga

Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1

肌动蛋白机械敏感性受与细胞周期依赖性激酶-1 的直接相互作用调节

Rosemarie E Gough, Matthew C Jones, Thomas Zacharchenko, Shimin Le, Miao Yu, Guillaume Jacquemet, Ste P Muench, Jie Yan, Jonathan D Humphries, Claus Jørgensen, Martin J Humphries, Benjamin T Goult

Functionalization of the BCL6 BTB domain into a noncovalent crystallization chaperone

将BCL6 BTB结构域功能化为非共价结晶伴侣

Zacharchenko, Thomas; Wright, Stephanie

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

SHANK 蛋白通过直接与 Rap1 和 R-Ras 相互作用来限制整合素活化

Johanna Lilja #, Thomas Zacharchenko #, Maria Georgiadou, Guillaume Jacquemet, Nicola De Franceschi, Emilia Peuhu, Hellyeh Hamidi, Jeroen Pouwels, Victoria Martens, Fatemeh Hassani Nia, Malte Beifuss, Tobias Boeckers, Hans-Juergen Kreienkamp, Igor L Barsukov, Johanna Ivaska

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex.

Talin 对 LD 基序的识别:Talin-DLC1 复合物的结构

Zacharchenko Thomas, Qian Xiaolan, Goult Benjamin T, Jethwa Devina, Almeida Teresa B, Ballestrem Christoph, Critchley David R, Lowy Douglas R, Barsukov Igor L