日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A model for Crohn's disease post-ileal resection fibrosis development using human ileal enteroids and myofibroblasts

利用人回肠类器官和肌成纤维细胞构建克罗恩病回肠切除术后纤维化发展模型

Yoo, Jun Hwan; Choi, Yoon Jeong; Pinchuk, Iryna V; Powell, Don W; Zachos, Nicholas C; Donowitz, Mark

Defining a 'cells to society' research framework for appendiceal tumours

为阑尾肿瘤构建“从细胞到社会”的研究框架

Holowatyj, Andreana N; Overman, Michael J; Votanopoulos, Konstantinos I; Lowy, Andrew M; Wagner, Patrick; Washington, Mary K; Eng, Cathy; Foo, Wai Chin; Goldberg, Richard M; Hosseini, Mojgan; Idrees, Kamran; Johnson, Douglas B; Shergill, Ardaman; Ward, Erin; Zachos, Nicholas C; Shelton, Deborah

A Novel Peptide Prevents Enterotoxin- and Inflammation-Induced Intestinal Fluid Secretion by Stimulating Sodium-Hydrogen Exchanger 3 Activity

一种新型肽通过刺激钠氢交换器3的活性来阻止肠毒素和炎症诱导的肠液分泌。

Zachos, Nicholas C; Vaughan, Hannah; Sarker, Rafiquel; Est-Witte, Savannah; Chakraborty, Molee; Baetz, Nicholas W; Yu, Hongzhe; Yarov-Yarovoy, Vladimir; McNamara, George; Green, Jordan J; Tse, Chung-Ming; Donowitz, Mark

Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers

假结核耶尔森菌YopE可阻止M细胞摄取,并诱导人回肠类器官来源的单层细胞中M细胞的排出。

Fasciano, Alyssa C; Dasanayake, Gaya S; Estes, Mary K; Zachos, Nicholas C; Breault, David T; Isberg, Ralph R; Tan, Shumin; Mecsas, Joan

Regenerative Intestinal Stem Cells Induced by Acute and Chronic Injury: The Saving Grace of the Epithelium?

急性和慢性损伤诱导的肠道干细胞再生:上皮的救星?

Rees, William D; Tandun, Rene; Yau, Enoch; Zachos, Nicholas C; Steiner, Theodore S

Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

上皮细胞WNT2B和沙漠刺猬蛋白是细菌细胞毒素损伤后人类结肠类器官再生所必需的

In, Julie G; Yin, Jianyi; Atanga, Roger; Doucet, Michele; Cole, Robert N; DeVine, Lauren; Donowitz, Mark; Zachos, Nicholas C; Blutt, Sarah E; Estes, Mary K; Kovbasnjuk, Olga

Using Enteroendocrine Cell-Enriched Human Enteroids to Evaluate Responses to Gut Stimuli

利用富含肠内分泌细胞的人类肠类器官评估对肠道刺激的反应

Zachos, Nicholas C

Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors

利用体外和离体肠道模型研究宿主-微生物组相互作用和急性应激

Pearce, Sarah C; Coia, Heidi G; Karl, J P; Pantoja-Feliciano, Ida G; Zachos, Nicholas C; Racicot, Kenneth

Enterotoxigenic Escherichia coli is phagocytosed by macrophages underlying villus-like intestinal epithelial cells: modeling ex vivo innate immune defenses of the human gut

肠毒素性大肠杆菌被绒毛状肠上皮细胞下方的巨噬细胞吞噬:模拟人肠道的体外固有免疫防御

Noel, Gaelle; Doucet, Michele; Nataro, James P; Kaper, James B; Zachos, Nicholas C; Pasetti, Marcela F

Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins

苯并嘧啶并吡咯并噁嗪二酮CFTR抑制剂(R)-BPO-27用于治疗细菌肠毒素引起的腹泻的抗分泌治疗

Cil, Onur; Phuan, Puay-Wah; Gillespie, Anne Marie; Lee, Sujin; Tradtrantip, Lukmanee; Yin, Jianyi; Tse, Ming; Zachos, Nicholas C; Lin, Ruxian; Donowitz, Mark; Verkman, Alan S