Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling
通过X射线晶体衍射分析不同中间体、31P-NMR光谱和反应路径建模,揭示了dUTPase中α-磷酸盐攻击的催化机制。
期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkt756
Barabás, Orsolya; Németh, Veronika; Bodor, Andrea; Perczel, András; Rosta, Edina; Kele, Zoltán; Zagyva, Imre; Szabadka, Zoltán; Grolmusz, Vince I; Wilmanns, Matthias; Vértessy, Beáta G