日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-guided design of partial agonists at an opioid receptor.

基于结构的阿片受体部分激动剂设计

Varga Balazs R, Bernhard Sarah M, El Daibani Amal, Zaidi Saheem A, Lam Jordy H, Aguilar Jhoan, Appourchaux Kevin, Nazarova Antonina L, Kouvelis Alexa, Shinouchi Ryosuke, Hammond Haylee R, Eans Shainnel O, Weinreb Violetta, Margolis Elyssa B, Fay Jonathan F, Huang Xi-Ping, Pradhan Amynah, Katritch Vsevolod, McLaughlin Jay P, Majumdar Susruta, Che Tao

Structure-guided design of a peripherally restricted chemogenetic system.

结构导向的外周限制性化学遗传系统设计

Kang Hye Jin, Krumm Brian E, Tassou Adrien, Geron Matan, DiBerto Jeffrey F, Kapolka Nicholas J, Gumpper Ryan H, Sakamoto Kensuke, Dewran Kocak D, Olsen Reid H J, Huang Xi-Ping, Zhang Shicheng, Huang Karen L, Zaidi Saheem A, Nguyen MyV T, Jo Min Jeong, Katritch Vsevolod, Fay Jonathan F, Scherrer Grégory, Roth Bryan L

Structure-based design of bitopic ligands for the µ-opioid receptor

基于结构的μ-阿片受体双位点配体设计

Faouzi, Abdelfattah; Wang, Haoqing; Zaidi, Saheem A; DiBerto, Jeffrey F; Che, Tao; Qu, Qianhui; Robertson, Michael J; Madasu, Manish K; El Daibani, Amal; Varga, Balazs R; Zhang, Tiffany; Ruiz, Claudia; Liu, Shan; Xu, Jin; Appourchaux, Kevin; Slocum, Samuel T; Eans, Shainnel O; Cameron, Michael D; Al-Hasani, Ream; Pan, Ying Xian; Roth, Bryan L; McLaughlin, Jay P; Skiniotis, Georgios; Katritch, Vsevolod; Kobilka, Brian K; Majumdar, Susruta

Harnessing Ion-Binding Sites for GPCR Pharmacology

利用离子结合位点进行GPCR药理学研究

Zarzycka, Barbara; Zaidi, Saheem A; Roth, Bryan L; Katritch, Vsevolod

Understanding molecular interactions between scavenger receptor A and its natural product inhibitors through molecular modeling studies.

通过分子建模研究了解清道夫受体 A 与其天然产物抑制剂之间的分子相互作用

Pagare Piyusha P, Zaidi Saheem A, Zhang Xiaomei, Li Xia, Yu Xiaofei, Wang Xiang-Yang, Zhang Yan

Small molecule inhibits activity of scavenger receptor A: Lead identification and preliminary studies

小分子抑制清道夫受体A的活性:先导化合物筛选和初步研究

Yuan, Yunyun; Li, Xia; Zaidi, Saheem A; Arnatt, Christopher K; Yu, Xiaofei; Guo, Chunqing; Wang, Xiang-Yang; Zhang, Yan

5-Hydroxy-2-(2-phenylethyl)chromone (5-HPEC): a novel non-nitrogenous ligand for 5-HT2B receptor

5-羟基-2-(2-苯乙基)色酮 (5-HPEC):一种新型的5-HT2B受体非含氮配体

Williams, Dwight A; Zaidi, Saheem A; Zhang, Yan

Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of mu opioid receptor selective antagonists

通过对接阿片受体晶体结构和定点诱变研究,表征6α-和6β-N-杂环取代的纳曲沙明衍生物的结合模式:将“信息-地址”概念应用于μ阿片受体选择性拮抗剂的开发

Zaidi, Saheem A; Arnatt, Christopher K; He, Hengjun; Selley, Dana E; Mosier, Philip D; Kellogg, Glen E; Zhang, Yan