Zaika Alexander相关文献与解析，生知库 | 链接生命科学的每一步

Lu, Heng; Ballout, Farah; Chen, Lei; Peng, Dunfa; Chen, Zheng; Soutto, Mohammed; Cao, Longlong; Thangaretnam, Krishnapriya; Gokulan, Ravindran Caspa; Wang, Timothy C; Que, Jianwen; Giordano, Silvia; Washington, Mary Kay; Chen, Xi Steven; Sun, Xiaodian; Ban, Yuguang; McDonald, Oliver Gene; Zaika, Alexander; El-Rifai, Wael

肿瘤

SOX

肿瘤免疫

SOX9

发表日期：2026

文献求助收藏

WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma

WEE1稳定MYC，从而促进食管腺癌的治疗耐药性

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2026.218418

Thangaretnam, Krishnapriya; Islam, Md Obaidul; Lv, Jialun; Zhang, Zhenzhen; Chen, Lei; Ballout, Farah; Lu, Heng; Peng, Dunfa; Zaika, Alexander; El-Rifai, Wael; Giordano, Silvia; Ban, Yuguang; Bilbao, Daniel; Chen, Zheng

Point-of-Care CagA Antibody Positivity and Its Association with Precancerous Gastric Changes

即时检测CagA抗体阳性及其与胃癌前病变的关系

期刊:Cancer Prevention Research

影响因子:2.6

doi:10.1158/1940-6207.CAPR-25-0325

Kumar, Shria; Goldberg, David S; Zaika, Elena; Yow, Maria V; Brown, Chloe M; Paulrasu, Kodisundaram; Montgomery, Elizabeth A; Morgan, Douglas R; El-Rifai, Wael; Zaika, Alexander

CDK1 drives SOX9-mediated chemotherapeutic resistance in gastric cancer.

CDK1 驱动 SOX9 介导的胃癌化疗耐药性。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-025-03523-3

Al-Mathkour Marwah, Chen Zheng, Poveda Julio, Cao Longlong, McDonald Oliver G, Peng Dunfa, Soutto Mohammed, Chen Zhibin, Lu Heng, Guo Yan, Kumar Shria, Zaika Alexander, Giordano Silvia, Zhu Shoumin, El-Rifai Wael

Chronic Gastroesophageal Reflux Dysregulates Proteostasis in Esophageal Epithelial Cells.

慢性胃食管反流会扰乱食管上皮细胞的蛋白质稳态

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2024.101434

Paulrasu Kodisundaram, Caspa Gokulan Ravindran, El-Rifai Wael, Chen Zhibin, Que Jianwen, Wang Timothy C, Boutaud Olivier G, Briegel Karoline, Dikalov Sergey I, Garcia-Buitrago Monica T, Zaika Alexander I

细胞生物学

发表日期：2025

文献求助收藏

Autoimmunity and H. pylori infection cooperatively promote epithelial tumorigenic differentiation and systemic immune modulation

自身免疫和幽门螺杆菌感染协同促进上皮肿瘤分化和全身免疫调节。

期刊:

影响因子:

doi:10.1101/2025.11.23.690054

Vazquez, Emily N; Lozano, Clarisel; Honan, Amanda M; Zaika, Elena; Houghton, JeanMarie; El-Rifai, Wael; Zaika, Alexander; Chen, Zhibin

SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation

SOX9 受 AURKA 调控，响应幽门螺杆菌感染，其调控机制是通过 EIF4E 介导的帽依赖性翻译。

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2024.216939

Gomaa, Ahmed; Maacha, Selma; Peng, Dunfa; Soutto, Mohammed; Genoula, Melanie; Bhat, Nadeem; Cao, Longlong; Zhu, Shoumin; Castells, Antoni; Chen, Zhibin; Zaika, Alexander; McDonald, Oliver G; El-Rifai, Wael

Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma

反流条件通过APE1氧化还原功能诱导食管腺癌中E-钙黏蛋白裂解和上皮间质转化（EMT）。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2023-329455

Lu, Heng; Cao, Long Long; Ballout, Farah; Belkhiri, Abbes; Peng, DunFa; Chen, Lei; Chen, Zheng; Soutto, Mohammed; Wang, Timothy C; Que, Jianwen; Giordano, Silvia; Washington, Mary Kay; Chen, Steven; McDonald, Oliver Gene; Zaika, Alexander; El-Rifai, Wael

Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma

在食管腺癌中，DLL1介导的NOTCH信号通路激活是由APE1氧化还原依赖性NF-κB激活所致。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2022-327076

Chen, Lei; Lu, Heng; Peng, Dunfa; Cao, Long Long; Ballout, Farah; Srirmajayam, Kannappan; Chen, Zheng; Bhat, Ajaz; Wang, Timothy C; Capobianco, Anthony; Que, Jianwen; McDonald, Oliver Gene; Zaika, Alexander; Zhang, Shutian; El-Rifai, Wael

Urgent need to mitigate disparities in federal funding for cancer research

迫切需要缩小联邦政府对癌症研究的资助差距

期刊:Jnci-Journal of the National Cancer Institute

影响因子:7.2

doi:10.1093/jnci/djad097

Haghighat, Shida; Jiang, Chunsu; El-Rifai, Wael; Zaika, Alexander; Goldberg, David S; Kumar, Shria

Targeting APE1-Redox Function Reverses SOX9-mediated Chemoresistance in Esophageal Adenocarcinoma

靶向 APE1 氧化还原功能可逆转 SOX9 介导的食管腺癌化疗耐药性

WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma

WEE1稳定MYC，从而促进食管腺癌的治疗耐药性

Point-of-Care CagA Antibody Positivity and Its Association with Precancerous Gastric Changes

即时检测CagA抗体阳性及其与胃癌前病变的关系

CDK1 drives SOX9-mediated chemotherapeutic resistance in gastric cancer.

CDK1 驱动 SOX9 介导的胃癌化疗耐药性。

Chronic Gastroesophageal Reflux Dysregulates Proteostasis in Esophageal Epithelial Cells.

慢性胃食管反流会扰乱食管上皮细胞的蛋白质稳态

Autoimmunity and H. pylori infection cooperatively promote epithelial tumorigenic differentiation and systemic immune modulation

自身免疫和幽门螺杆菌感染协同促进上皮肿瘤分化和全身免疫调节。

SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation

SOX9 受 AURKA 调控，响应幽门螺杆菌感染，其调控机制是通过 EIF4E 介导的帽依赖性翻译。

Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma

反流条件通过APE1氧化还原功能诱导食管腺癌中E-钙黏蛋白裂解和上皮间质转化（EMT）。

Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma

在食管腺癌中，DLL1介导的NOTCH信号通路激活是由APE1氧化还原依赖性NF-κB激活所致。

Urgent need to mitigate disparities in federal funding for cancer research

迫切需要缩小联邦政府对癌症研究的资助差距