日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrated proteomic analysis identifies TYMS-dependent AMPK-mTOR signaling in pancreatic neuroendocrine tumors

整合蛋白质组学分析揭示胰腺神经内分泌肿瘤中TYMS依赖的AMPK-mTOR信号通路

Vijayakurup, Vinod; Meyer, Benjamin; Rizvi, Syeda Rida; Kievit, Kara H; Hyder, Iram; Koh, Jin; Feely, Michael; Guijarro, Maria V; Kaye, Frederic J; Zajac-Kaye, Maria

CerS2 is a druggable target in triple-negative breast cancer.

CerS2 是三阴性乳腺癌的一个可药物靶点

Alatawi Hissah, Nair Haritha H, Ai Lingbao, Mahmud Iqbal, Gour Abhishek, Singh Amandeep, Baek Doohyun, Yan Bowen, Maharjan Chandra K, Zhang Weizhou, Law Brian K, Zajac-Kaye Maria, Vulpe Christopher, Guryanova Olga A, Sharma Arun K, Garrett Timothy J, Sharma Abhisheak, Heldermon Coy D, Hong Sukwon, Narayan Satya

Corrigendum: Targeting thymidylate synthase enhances the chemosensitivity of triple-negative breast cancer towards 5-FU-based combinatorial therapy

更正:靶向胸苷酸合成酶可增强三阴性乳腺癌对基于 5-氟尿嘧啶的联合疗法的化疗敏感性

Haritha, Nair Hariprasad; Nawab, Akbar; Vijayakurup, Vinod; Anto, Nikhil Ponnoor; Liju, Vijayasteltar B; Alex, Vijai V; Amrutha, Areekkara Nisthul; Aiswarya, Sreekumar U; Swetha, Mundanattu; Vinod, Balachandran S; Sundaram, Sankar; Guijarro, Maria V; Herlevich, Thomas; Krishna, Archana; Nestory, Nesteena K; Bava, Smitha V; Sadasivan, Chittalakkottu; Zajac-Kaye, Maria; Anto, Ruby John

BCL-X(L) PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS(G12C)-mutated cancers

BCL-X(L) PROTAC降解剂DT2216与sotorasib在KRAS(G12C)突变癌症的临床前模型中具有协同作用

Khan, Sajid; Wiegand, Janet; Zhang, Peiyi; Hu, Wanyi; Thummuri, Dinesh; Budamagunta, Vivekananda; Hua, Nan; Jin, Lingtao; Allegra, Carmen J; Kopetz, Scott E; Zajac-Kaye, Maria; Kaye, Frederic J; Zheng, Guangrong; Zhou, Daohong

Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy

靶向胸苷酸合成酶可增强三阴性乳腺癌对基于5-氟尿嘧啶的联合疗法的化疗敏感性

Haritha, Nair Hariprasad; Nawab, Akbar; Vijayakurup, Vinod; Anto, Nikhil Ponnoor; Liju, Vijayasteltar B; Alex, Vijai V; Amrutha, Areekkara Nisthul; Aiswarya, Sreekumar U; Swetha, Mundanattu; Vinod, Balachandran S; Sundaram, Sankar; Guijarro, Maria V; Herlevich, Thomas; Krishna, Archana; Nestory, Nesteena K; Bava, Smitha V; Sadasivan, Chittalakkottu; Zajac-Kaye, Maria; Anto, Ruby John

Microbial marauders: pancreatic microbiota and its impact on carcinogenesis

微生物掠夺者:胰腺微生物群及其对致癌作用的影响

Thomas, Ryan M; Zajac-Kaye, Maria

Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors

利用衣壳优化的AAV8载体在胰腺和胰腺肿瘤中高效递送和表达基因

Chen, Min; Maeng, Kyungah; Nawab, Akbar; Francois, Rony A; Bray, Julie K; Reinhard, Mary K; Boye, Sanford L; Hauswirth, William W; Kaye, Frederic J; Aslanidi, Georgiy; Srivastava, Arun; Zajac-Kaye, Maria

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

腺样囊性癌的统一基因特征可识别出平行存在的MYB依赖性和MYB非依赖性治疗靶点。

Gao, Ruli; Cao, Chunxia; Zhang, Min; Lopez, Maria-Cecilia; Yan, Yuanqing; Chen, Zirong; Mitani, Yoshitsugu; Zhang, Li; Zajac-Kaye, Maria; Liu, Bin; Wu, Lizi; Renne, Rolf; Baker, Henry V; El-Naggar, Adel; Kaye, Frederic J

Current understanding of the molecular biology of pancreatic neuroendocrine tumors

目前对胰腺神经内分泌肿瘤分子生物学的认识

Zhang, Jianliang; Francois, Rony; Iyer, Renuka; Seshadri, Mukund; Zajac-Kaye, Maria; Hochwald, Steven N

Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo

抑制cMET和IGF-1R与FAK的相互作用可有效降低体外和体内胰腺癌细胞的生长。

Ucar, Deniz A; Magis, Andrew T; He, Di-Hua; Lawrence, Nicholas J; Sebti, Said M; Kurenova, Elena; Zajac-Kaye, Maria; Zhang, Jianliang; Hochwald, Steven N