日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Generation of the ICGi019-B-1 and ICGi019-B-2 lines via correction of the p.Met659Ile (c.1977G>A) variant in MYH7 of patient-specific induced pluripotent stem cells using CRISPR/Cas9

利用 CRISPR/Cas9 技术,通过校正患者特异性诱导多能干细胞中 MYH7 基因的 p.Met659Ile (c.1977G>A) 变异,构建了 ICGi019-B-1 和 ICGi019-B-2 细胞系。

Shulgina, A E; Pavlova, S V; Minina, J M; Zakian, S M; Dementyeva, E V

Isogenic induced pluripotent stem cell line ICGi036-A-1 from a patient with familial hypercholesterolaemia, derived by correcting a pathogenic variant of the gene LDLR c.530C>T

从一名家族性高胆固醇血症患者中获得的同源诱导多能干细胞系ICGi036-A-1,是通过纠正LDLR基因c.530C>T的致病性变异而获得的。

Zueva, A S; Shevchenko, A I; Medvedev, S P; Elisaphenko, E A; Sleptcov, A A; Nazarenko, M S; Tmoyan, N A; Zakian, S M; Zakharova, I S

Generation and characterisation of seven induced pluripotent stem cell lines from two patients with Parkinson's disease carrying the pathological variant c.1087G>T of the LGR4 gene.

从两名患有帕金森病且携带 LGR4 基因致病变异 c.1087G>T 的患者中生成和鉴定了七种诱导多能干细胞系

Podvysotskaya V S, Grigor'eva E V, Malakhova A A, Minina J M, Vyatkin Y V, Khabarova E A, Rzaev J A, Medvedev S P, Kovalenko L V, Zakian S M

Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated with the pathological variant c.2013T>G in the MAPT gene.

从患有额颞叶痴呆伴帕金森症-17 的患者中生成和表征两种诱导多能干细胞系(ICGi052-A 和 ICGi052-B),该患者携带 MAPT 基因中的病理变异 c.2013T>G

Grigor'eva E V, Malakhova A A, Yarkova E S, Minina J M, Vyatkin Y V, Nadtochy J A, Khabarova E A, Rzaev J A, Medvedev S P, Zakian S M

PARP1 Gene Knockout Suppresses Expression of DNA Base Excision Repair Genes

PARP1基因敲除抑制DNA碱基切除修复基因的表达

Zakharenko, A L; Malakhova, A A; Dyrkheeva, N S; Okorokova, L S; Medvedev, S P; Zakian, S M; Kabilov, M R; Tupikin, A A; Lavrik, O I