日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening

从 DNA 编码化学库筛选中开发小分子非共价冠状病毒 3CL 蛋白酶抑制剂

Hengrui Liu, Arie Zask, Farhad Forouhar, Sho Iketani, Alana Williams, Daniel R Vaz, Dahlya Habashi, Karenna Choi, Samuel J Resnick, Seo Jung Hong, David H Lovett, Tian Bai, Alejandro Chavez, David D Ho, Brent R Stockwell3

Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers.

亚型选择性异戊二烯化异黄酮可破坏 MYCN 扩增癌症的调控驱动因素

Stokes Michael E, Vasciaveo Alessandro, Small Jonnell Candice, Zask Arie, Reznik Eduard, Smith Nailah, Wang Qian, Daniels Jacob, Forouhar Farhad, Rajbhandari Presha, Califano Andrea, Stockwell Brent R

Implementation of a digital exercise programme in health services to prevent falls in older people

在医疗服务中实施数字化运动计划,以预防老年人跌倒

Taylor, Morag E; Ambrens, Meghan; Hawley-Hague, Helen; Todd, Christopher; Close, Jacqueline C T; Lord, Stephen R; Clemson, Lindy; Lung, Thomas; Berlowitz, David; Blennerhassett, Jannette; Dayhew, Julia; Gluchowski, Ashley; Hodge, Wendy; Johnson, Pamela; Lasrado, Reena; Merlene, Marita; Miles, Lillian; O'Rourke, Sandra; Said, Catherine M; White, Leanne; Wilson, Nicola; Zask, Avigdor; Delbaere, Kim

Supporting adolescents' participation in muscle-strengthening physical activity: protocol for the 'Resistance Training for Teens' (RT4T) hybrid type III implementation-effectiveness trial

支持青少年参与肌肉强化体育活动:青少年阻力训练(RT4T)混合型III型实施效果试验方案

Kelly, Hayden Thomas; Smith, Jordan James; Verdonschot, Angeliek; Kennedy, Sarah Grace; Scott, Joseph J; McKay, Heather; Nathan, Nicole; Sutherland, Rachel; Morgan, Philip James; Salmon, Jo; Penney, Dawn; Boyer, James; Lloyd, Rhodri S; Oldmeadow, Christopher; Reeves, Penny; Pursey, Kirrilly; Hua, Myna; Longmore, Sarah; Norman, Jennifer; Voukelatos, Alexander; Zask, Avigdor; Lubans, David Revalds

Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia

NT5C2 的药物抑制可逆转急性淋巴细胞白血病中 6-MP 耐药性的遗传和非遗传驱动因素

Clara Reglero #, Chelsea L Dieck #, Arie Zask, Farhad Forouhar, Anouchka P Laurent, Wen-Hsuan W Lin, Robert Albero, Hannah I Miller, Cindy Ma, Julie M Gastier-Foster, Mignon L Loh, Liang Tong, Brent R Stockwell, Teresa Palomero, Adolfo A Ferrando

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

开发优化的 SARS-CoV-2 3CL 蛋白酶类药物小分子抑制剂用于治疗 COVID-19

Hengrui Liu, Sho Iketani, Arie Zask, Nisha Khanizeman, Eva Bednarova, Farhad Forouhar, Brandon Fowler, Seo Jung Hong, Hiroshi Mohri, Manoj S Nair, Yaoxing Huang, Nicholas E S Tay, Sumin Lee, Charles Karan, Samuel J Resnick, Colette Quinn, Wenjing Li, Henry Shion, Xin Xia, Jacob D Daniels, Michelle B

Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity

冠状病毒 3CL 蛋白酶抑制剂可保护细胞免受蛋白酶介导的细胞毒性

Samuel J Resnick, Sho Iketani, Seo Jung Hong, Arie Zask, Hengrui Liu, Sungsoo Kim, Schuyler Melore, Fang-Yu Lin, Manoj S Nair, Yaoxing Huang, Sumin Lee, Nicholas E S Tay, Tomislav Rovis, Hee Won Yang, Li Xing, Brent R Stockwell, David D Ho, Alejandro Chavez

A simplified cell-based assay to identify coronavirus 3CL protease inhibitors

一种简化的基于细胞的检测方法,用于鉴定冠状病毒 3CL 蛋白酶抑制剂

Samuel J Resnick, Sho Iketani, Seo Jung Hong, Arie Zask, Hengrui Liu, Sungsoo Kim, Schuyler Melore, Manoj S Nair, Yaoxing Huang, Nicholas E S Tay, Tomislav Rovis, Hee Won Yang, Brent R Stockwell, David D Ho, Alejandro Chavez

Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents

MAP4 激酶抑制剂作为运动神经元保护剂的开发

Pieter H Bos, Emily R Lowry, Jonathon Costa, Sebastian Thams, Alejandro Garcia-Diaz, Arie Zask, Hynek Wichterle, Brent R Stockwell

Multivalent Small-Molecule Pan-RAS Inhibitors

多价小分子泛RAS抑制剂

Matthew E Welsch ,Anna Kaplan ,Jennifer M Chambers ,Michael E Stokes ,Pieter H Bos ,Arie Zask ,Yan Zhang ,Marta Sanchez-Martin ,Michael A Badgley ,Christine S Huang ,Timothy H Tran ,Hemanth Akkiraju ,Lewis M Brown ,Renu Nandakumar ,Serge Cremers ,Wan Seok Yang ,Liang Tong ,Kenneth P Olive ,Adolfo Ferrando ,Brent R Stockwell