日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq

利用DMS-MaPseq技术检测活体人类细胞中端粒酶RNA的结构异质性

Forino, Nicholas M; Woo, Jia Zheng; Zaug, Arthur J; Jimenez, Arcelia Gonzalez; Edelson, Eva; Cech, Thomas R; Rouskin, Silvi; Stone, Michael D

POT1 recruits and regulates CST-Polα/primase at human telomeres.

POT1 在人类端粒处招募和调节 CST-Polα/引物酶

Cai Sarah W, Takai Hiroyuki, Zaug Arthur J, Dilgen Teague C, Cech Thomas R, Walz Thomas, de Lange Titia

Reconstitution of a telomeric replicon organized by CST

CST 组织的端粒复制子重建

Arthur J Zaug, Karen J Goodrich, Jessica J Song, Ashley E Sullivan, Thomas R Cech

CST does not evict elongating telomerase but prevents initiation by ssDNA binding

CST 不会驱逐延长端粒酶,但会阻止 ssDNA 结合启动

Arthur J Zaug, Ci Ji Lim, Conner L Olson, Maria T Carilli, Karen J Goodrich, Deborah S Wuttke, Thomas R Cech

Dynamics of human telomerase recruitment depend on template-telomere base pairing

人类端粒酶募集的动态过程取决于模板-端粒碱基配对

Jens C Schmidt ,Arthur J Zaug ,Regina Kufer ,Thomas R Cech

Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres

活细胞成像揭示端粒酶募集端粒的动态

Jens C Schmidt, Arthur J Zaug, Thomas R Cech

A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression

一种基于 CRISPR-Cas9 的新型两步基因组编辑策略为端粒酶作用和 TERT 基因表达提供了新的见解

Linghe Xi ,Jens C Schmidt ,Arthur J Zaug ,Dante R Ascarrunz ,Thomas R Cech

Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance

疾病突变分析确定了 DAXX 在端粒酶调控和端粒维护中的新功能

Mengfan Tang, Yujing Li, Yi Zhang, Yuxi Chen, Wenjun Huang, Dan Wang, Arthur J Zaug, Dan Liu, Yong Zhao, Thomas R Cech, Wenbin Ma, Zhou Songyang

Many disease-associated variants of hTERT retain high telomerase enzymatic activity

许多与疾病相关的 hTERT 变体保留了较高的端粒酶活性

Arthur J Zaug, Sharon M Crary, Matthew Jesse Fioravanti, Kristina Campbell, Thomas R Cech

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

端粒蛋白 TPP1 的 TEL 补丁介导端粒酶的募集和加工性

Jayakrishnan Nandakumar, Caitlin F Bell, Ina Weidenfeld, Arthur J Zaug, Leslie A Leinwand, Thomas R Cech