日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non-small cell lung cancer

PP2A分子胶克服了KRAS突变型非小细胞肺癌的RAS/MAPK抑制剂耐药性

Raines, Brynne; Tseng-Rogenski, Stephanie; Dowdican, Amanda C; Peris, Irene; Hinderman, Matthew; Zawacki, Kaitlin P; Barrie, Kelsey; Hodges Onishi, Gabrielle; Dymond, Alexander M; Luther, Tahra K; Musser, Sydney; Karaj Majchrowski, Behirda; Brenner, J Chad; Ahmed, Aqila; Taylor, Derek J; O'Connor, Caitlin M; Narla, Goutham

The SRG RAT® supports human cell xenotransplantation through enhanced tumor microenvironment interactions

SRG RAT® 通过增强肿瘤微环境相互作用来支持人类细胞异种移植。

O'Connor, Caitlin M; Zawacki, Kaitlin P; Durrant, Jessica R; Barrie, Kelsey; Walton, R Grace; King, Dana; Onishi, Gabrielle Hodges; Noto, Fallon K; Hinderman, Matthew; Begemann, Diane; Branyan, Taylor; Panwell, Karah; DiFeo, Analisa; Schlosser, Michael J; Narla, Goutham

PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis

PP2A 调控通过 mPTP 依赖性细胞凋亡克服慢性淋巴细胞白血病的多药耐药性

Jayappa, Kallesh D; Tran, Brian; Gordon, Vicki L; Morris, Christopher; Saha, Shekhar; Farrington, Caroline C; O'Connor, Caitlin M; Zawacki, Kaitlin P; Isaac, Krista M; Kester, Mark; Bender, Timothy P; Williams, Michael E; Portell, Craig A; Weber, Michael J; Narla, Goutham

Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin-MLL Interaction with Strong In Vivo Antitumor Activity.

发现 M-808 是一种高效的共价小分子抑制剂,可抑制 Menin-MLL 相互作用,并具有很强的体内抗肿瘤活性

Xu Shilin, Aguilar Angelo, Huang Liyue, Xu Tianfeng, Zheng Ke, McEachern Donna, Przybranowski Sally, Foster Caroline, Zawacki Kaitlin, Liu Zhaomin, Chinnaswamy Krishnapriya, Stuckey Jeanne, Wang Shaomeng