日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evaluation of a Combinatorial Immunotherapy Regimen That Can Cure Mice Bearing MYCN-Driven High-Risk Neuroblastoma That Resists Current Clinical Therapy

评估一种联合免疫疗法方案,该方案可治愈携带 MYCN 驱动的高危神经母细胞瘤且对现有临床疗法耐药的小鼠。

Zebertavage, Lauren; Schopf, Allison; Nielsen, Megan; Matthews, Joel; Erbe, Amy K; Aiken, Taylor J; Katz, Sydney; Sun, Claire; Witt, Cole M; Rakhmilevich, Alexander L; Sondel, Paul M

Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help

肿瘤驻留记忆 CD8 T 细胞和伴随的肿瘤免疫独立于 CD4 帮助而发展

Terry R Medler, Gwen Kramer, Shelly Bambina, Andrew J Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka R Crittenden, Michael J Gough

Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma

针对免疫冷鼠神经母细胞瘤9464D-GD2的有效联合放射免疫疗法的机制

Aiken, Taylor J; Erbe, Amy K; Zebertavage, Lauren; Komjathy, David; Feils, Arika S; Rodriguez, Matthew; Stuckwisch, Ashley; Gillies, Stephen D; Morris, Zachary S; Birstler, Jen; Rakhmilevich, Alexander L; Sondel, Paul M

The Dynamic Entropy of Tumor Immune Infiltrates: The Impact of Recirculation, Antigen-Specific Interactions, and Retention on T Cells in Tumors

肿瘤免疫浸润的动态熵:再循环、抗原特异性相互作用和滞留对肿瘤内T细胞的影响

Blair, Tiffany C; Alice, Alejandro F; Zebertavage, Lauren; Crittenden, Marka R; Gough, Michael J

Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity

辐射导致 NLRC5 转录上调,从而驱动癌细胞中 STING 和干扰素非依赖性的 MHC-I 表达以及 T 细胞细胞毒性

Lauren K Zebertavage, Alejandro Alice, Marka R Crittenden, Michael J Gough

Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma

阻断成纤维细胞活化蛋白联合放射治疗在小鼠胰腺腺癌模型中的作用

Andrew J Gunderson, Tomoko Yamazaki, Kayla McCarty, Michaela Phillips, Alejandro Alice, Shelly Bambina, Lauren Zebertavage, David Friedman, Benjamin Cottam, Pippa Newell, Michael J Gough, Marka R Crittenden, Pieter Van der Veken, Kristina H Young

A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity

一种基于微生物的癌症疫苗,用于诱导 EGFRvIII 特异性 CD8+ T 细胞和抗肿瘤免疫

Lauren Zebertavage, Shelly Bambina, Jessica Shugart, Alejandro Alice, Kyra D Zens, Peter Lauer, Bill Hanson, Michael J Gough, Marka R Crittenden, Keith S Bahjat

Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity

放射疗法和检查点抑制剂治愈肿瘤取决于预先存在的免疫力

Marka R Crittenden, Lauren Zebertavage, Gwen Kramer, Shelly Bambina, David Friedman, Victoria Troesch, Tiffany Blair, Jason R Baird, Alejandro Alice, Michael J Gough