日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EVC protein regulates Sonic hedgehog signaling during human intervertebral disc development and degeneration.

EVC蛋白在人类椎间盘发育和退化过程中调节Sonic hedgehog信号传导。

Wu Zihan, Shaw Lizzy, Dube Christabel T, Ionescu Andra-Maria, Qiu Tengyang, Tierney Anna L, Baird Pauline, Patel Sonal, Zeef Leo A H, Birchall Lindsay J, Jennings Rachel E, Hanley Neil A, Unwin Richard D, Hoyland Judith A, Richardson Stephen M

The tumour immune microenvironment is enriched but suppressed in vestibular schwannoma compared to meningioma: therapeutic implications for NF2-related schwannomatosis

与脑膜瘤相比,前庭神经鞘瘤的肿瘤免疫微环境富集但受到抑制:对NF2相关神经鞘瘤病的治疗意义

Gregory, Grace E; Haley, Michael J; Jones, Adam Paul; Zeef, Leo A H; Evans, D Gareth; King, Andrew T; Paszek, Pawel; Couper, Kevin N; Brough, David; Pathmanaban, Omar N

Gene Expression in Muscle-Invasive and Non-Muscle-Invasive Bladder Cancer Cells Exposed to Hypoxia

缺氧条件下肌层浸润性和非肌层浸润性膀胱癌细胞的基因表达

Shabbir, Rekaya; Quiles, Conrado G; Lane, Brian; Zeef, Leo; Hoskin, Peter J; Choudhury, Ananya; West, Catharine M L; Smith, Tim A D

Unveiling the genetic basis of the low pH response in the acidophilic yeast Maudiozyma bulderi as a potential host for biorefinery

揭示嗜酸酵母 Maudiozyma bulderi 低 pH 响应的遗传基础,使其成为生物炼制的潜在宿主

Balarezo-Cisneros, Laura Natalia; Hanak, Alistair; Zeef, Leo; Mironov, Aleksandr; Valle, Fernando; Delneri, Daniela

Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations

人类多能干细胞衍生的肾脏类器官揭示杂合 HNF1B 相关发育不良性肾脏畸形的肾小管上皮病理生物学

Ioannis Bantounas, Kirsty M Rooney, Filipa M Lopes, Faris Tengku, Steven Woods, Leo A H Zeef, I-Hsuan Lin, Shweta Y Kuba, Nicola Bates, Sandra Hummelgaard, Katherine A Hillman, Silvia Cereghini, Adrian S Woolf, Susan J Kimber

Impact of inter-species hybridisation on antifungal drug response in the Saccharomyces genus

种间杂交对酵母属抗真菌药物反应的影响

Visinoni, Federico; Royle, William; Scholey, Rachel; Hu, Yue; Timouma, Soukaina; Zeef, Leo; Louis, Edward J; Delneri, Daniela

Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1

重编程免疫抑制性肿瘤微环境可成功清除对放射疗法和抗PD-1/PD-L1疗法耐药的肿瘤。

Mukherjee, Debayan; Romano, Erminia; Walshaw, Richard; Zeef, Leo A H; Banyard, Antonia; Kitcatt, Stephen J; Cheadle, Eleanor J; Tuomela, Karoliina; Pendharkar, Swati; Al-Deka, Aws; Salerno, Beatrice; Raby, Sophie; Mills, Ian G; Honeychurch, Jamie; Illidge, Tim M

Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease

昼夜节律紊乱促使肌成纤维细胞加速激活,这是非酒精性脂肪性肝病纤维化进展的潜在机制

Elliot Jokl, Jessica Llewellyn, Kara Simpson, Oluwatobi Adegboye, James Pritchett, Leo Zeef, Ian Donaldson, Varinder S Athwal, Huw Purssell, Oliver Street, Lucy Bennett, Indra Neil Guha, Neil A Hanley, Qing-Jun Meng, Karen Piper Hanley; ID-LIVER Consortium

The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma

散发性和 NF2 相关神经鞘瘤病前庭神经鞘瘤的肿瘤微环境相似

Grace E Gregory, Adam Paul Jones, Michael J Haley, Christopher Hoyle, Leo A H Zeef, I-Hsuan Lin, David J Coope, Andrew T King, D Gareth Evans, Pawel Paszek, Kevin N Couper, David Brough, Omar N Pathmanaban

Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture

不同表达PfEMP1的恶性疟原虫变体在共培养过程中诱导不同的内皮细胞转录反应。

Basim Othman ,Leo Zeef ,Tadge Szestak ,Zineb Rchiad ,Janet Storm ,Caroline Askonas ,Rohit Satyam ,Aymen Madkhali ,Michael Haley ,Simon Wagstaff ,Kevin Couper ,Arnab Pain ,Alister Craig