日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The Impact of the Injected Mass of the Gastrin-Releasing Peptide Receptor Antagonist on Uptake in Breast Cancer: Lessons from a Phase I Trial of [(99m)Tc]Tc-DB8

注射的胃泌素释放肽受体拮抗剂质量对乳腺癌摄取的影响：[(99m)Tc]Tc-DB8 I期试验的经验教训

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17081000
Bragina, Olga; Chernov, Vladimir; Larkina, Mariia; Varvashenya, Ruslan; Zelchan, Roman; Medvedeva, Anna; Ivanova, Anastasiya; Tashireva, Liubov; Maina, Theodosia; Nock, Berthold A; Kanellopoulos, Panagiotis; Sörensen, Jens; Orlova, Anna; Tolmachev, Vladimir
信号转导
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Phase I Clinical Study with the GRPR-Antagonist [(99m)Tc]Tc-DB8 for SPECT Imaging of Prostate Cancer: Does the Injected Peptide Mass Make a Difference?

使用 GRPR 拮抗剂 [(99m)Tc]Tc-DB8 进行 SPECT 成像检测前列腺癌的 I 期临床研究：注射的肽质量有影响吗？

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17101323
Orlova, Anna; Rybina, Anastasia; Medvedeva, Anna; Zelchan, Roman; Bragina, Olga; Tashireva, Liubov; Larkina, Maria; Varvashenya, Ruslan; Lushnikova, Nadejda; Kanellopoulos, Panagiotis; Maina, Theodosia; Nock, Berthold A; Tolmachev, Vladimir; Chernov, Vladimir
肿瘤
前列腺癌
肿瘤免疫
发表日期：2025
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Comparative Preclinical Evaluation of the Tumor-Targeting Properties of Radioiodine and Technetium-Labeled Designed Ankyrin Repeat Proteins for Imaging of Epidermal Growth Factor Receptor Expression in Malignant Tumors

放射性碘和锝标记的定制锚蛋白重复序列蛋白在恶性肿瘤表皮生长因子受体表达成像中的肿瘤靶向特性比较临床前评价

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262110609
Larkina, Mariia; Yanovich, Gleb; Hasnowo, Lutfi Aditya; Varvashenya, Ruslan; Yuldasheva, Feruza; Tretyakova, Maria; Plotnikov, Evgenii; Zelchan, Roman; Schulga, Alexey; Konovalova, Elena; Ziganshin, Rustam; Belousov, Mikhail V; Tolmachev, Vladimir; Deyev, Sergey M
信号转导
肿瘤
肿瘤免疫
发表日期：2025
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Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [(99m)Tc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study

利用新型肽基探针[(99m)Tc]Tc-BQ0413（对前列腺癌特异性膜抗原 (PSMA) 具有皮摩尔级亲和力）进行单光子发射计算机断层扫描成像检测前列腺癌患者PSMA表达：一项I/II期临床研究

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00637
Medvedeva, Anna; Chernov, Vladimir; Larkina, Maria; Rybina, Anastasiya; Zelchan, Roman; Bragina, Olga; Varvashenya, Ruslan; Zebzeeva, Olga; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir; Orlova, Anna
肿瘤
前列腺癌
肿瘤免疫
发表日期：2025
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Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [(99m)Tc]Tc(CO)(3)-(HE)(3)-Ec1 for Visualization of EpCAM-Expressing Lung Cancer

针对表达EpCAM的肺癌，对设计型锚蛋白重复序列蛋白[(99m)Tc]Tc(CO)3-(HE)3-Ec1进行I期临床评估

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers16162815
Zelchan, Roman; Chernov, Vladimir; Medvedeva, Anna; Rybina, Anastasia; Bragina, Olga; Mishina, Elizaveta; Larkina, Mariia; Varvashenya, Ruslan; Fominykh, Anastasia; Schulga, Alexey; Konovalova, Elena; Vorobyeva, Anzhelika; Orlova, Anna; Tashireva, Liubov; Deyev, Sergey M; Tolmachev, Vladimir
肺癌
肿瘤
肿瘤免疫
发表日期：2024
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Synthesis and Preclinical Evaluation of Urea-Based Prostate-Specific Membrane Antigen-Targeted Conjugates Labeled with (177)Lu

尿素基前列腺特异性膜抗原靶向缀合物（177Lu标记）的合成及临床前评价

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00070
Machulkin, Aleksei E; Petrov, Stanislav A; Bodenko, Vitalina; Larkina, Mariia S; Plotnikov, Evgenii; Yuldasheva, Feruza; Tretyakova, Maria; Bezverkhniaia, Ekaterina; Zyk, Nikolay Yu; Stasyuk, Elena; Zelchan, Roman; Majouga, Alexander G; Tolmachev, Vladimir; Orlova, Anna; Beloglazkina, Elena K; Yusubov, Mekhman S
发表日期：2024
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Phase I clinical evaluation of (99m)Tc-labeled Affibody molecule for imaging HER2 expression in breast cancer

99mTc标记的Affibody分子用于乳腺癌HER2表达成像的I期临床评估

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.86770
Bragina, Olga; Chernov, Vladimir; Larkina, Mariia; Rybina, Anstasiya; Zelchan, Roman; Garbukov, Eugeniy; Oroujeni, Maryam; Loftenius, Annika; Orlova, Anna; Sörensen, Jens; Frejd, Fredrik Y; Tolmachev, Vladimir
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2023
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Phase I Trial of [(99m)Tc]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

[(99m)Tc]Tc-maSSS-PEG(2)-RM26，一种胃泌素释放肽受体 (GRPR) 拮抗剂的铃蟾肽类似物，用于恶性肿瘤中 GRPR 表达的 SPECT 成像的 I 期试验

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers15061631
Chernov, Vladimir; Rybina, Anastasiya; Zelchan, Roman; Medvedeva, Anna; Bragina, Olga; Lushnikova, Nadejda; Doroshenko, Artem; Usynin, Evgeniy; Tashireva, Liubov; Vtorushin, Sergey; Abouzayed, Ayman; Rinne, Sara S; Sörensen, Jens; Tolmachev, Vladimir; Orlova, Anna
信号转导
肿瘤
肿瘤免疫
发表日期：2023
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The GRPR Antagonist [99mTc]Tc-maSSS-PEG2-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity

GRPR 拮抗剂 [99mTc]Tc-maSSS-PEG2-RM26 进入 I 期临床试验：试剂盒制备、特性和毒性

期刊:Diagnostics
影响因子:
doi:10.3390/diagnostics13091611
Ayman Abouzayed, Jesper Borin, Fanny Lundmark, Anastasiya Rybina, Sophia Hober, Roman Zelchan, Vladimir Tolmachev, Vladimir Chernov, Anna Orlova
毒理研究
发表日期：2023
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Phase I Clinical Trial Using [(99m)Tc]Tc-1-thio-D-glucose for Diagnosis of Lymphoma Patients

使用[(99m)Tc]Tc-1-硫代-D-葡萄糖诊断淋巴瘤患者的I期临床试验

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics14061274
Chernov, Vladimir; Dudnikova, Ekaterina; Zelchan, Roman; Medvedeva, Anna; Rybina, Anstasiya; Bragina, Olga; Goldberg, Viktor; Muravleva, Albina; Sörensen, Jens; Tolmachev, Vladimir
淋巴瘤
发表日期：2022
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