Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
胰腺癌的单细胞核和空间转录组分析揭示了与新辅助治疗相关的多细胞动态变化
期刊:Nature Genetics
影响因子:31.7
doi:10.1038/s41588-022-01134-8
William L Hwang # ,Karthik A Jagadeesh # ,Jimmy A Guo # ,Hannah I Hoffman # ,Payman Yadollahpour ,Jason W Reeves ,Rahul Mohan ,Eugene Drokhlyansky ,Nicholas Van Wittenberghe ,Orr Ashenberg ,Samouil L Farhi ,Denis Schapiro ,Prajan Divakar ,Eric Miller ,Daniel R Zollinger ,George Eng ,Jason M Schenkel ,Jennifer Su ,Carina Shiau ,Patrick Yu ,William A Freed-Pastor ,Domenic Abbondanza ,Arnav Mehta ,Joshua Gould ,Conner Lambden ,Caroline B M Porter ,Alexander Tsankov ,Danielle Dionne ,Julia Waldman ,Michael S Cuoco ,Lan Nguyen ,Toni Delorey ,Devan Phillips ,Jaimie L Barth ,Marina Kem ,Clifton Rodrigues ,Debora Ciprani ,Jorge Roldan ,Piotr Zelga ,Vjola Jorgji ,Jonathan H Chen ,Zackery Ely ,Daniel Zhao ,Kit Fuhrman ,Robin Fropf ,Joseph M Beechem ,Jay S Loeffler ,David P Ryan ,Colin D Weekes ,Cristina R Ferrone ,Motaz Qadan ,Martin J Aryee ,Rakesh K Jain ,Donna S Neuberg ,Jennifer Y Wo ,Theodore S Hong ,Ramnik Xavier ,Andrew J Aguirre ,Orit Rozenblatt-Rosen ,Mari Mino-Kenudson ,Carlos Fernandez-Del Castillo ,Andrew S Liss ,David T Ting ,Tyler Jacks ,Aviv Regev
