日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition.

成纤维细胞中条件性 BCL-2 表达促进持续性肺纤维化,而治疗性 BCL-2 抑制可逆转这一过程。

Redente Elizabeth F, Song Tengyao, Javkhlan Nomin, Edelman Benjamin L, Foster Daniel G, Wilson Jasmine A, Chakraborty Sangeeta, Cooley Joseph C, Gaurav Rohit, Saguthi Satria, Seibold Max A, Blumhagen Rachel Z, Schwartz David A, Yang Ivana V, Matsuda Jennifer, Bridges James P, Zemans Rachel L, Tuder Rubin M, Riches David W H

Prioritizing Therapeutic Targets for Interstitial Lung Disease: A Causal Mediation Analysis

间质性肺病治疗靶点优先排序:因果中介分析

Oldham, Justin; Molyneaux, Philip; Maddali, Manoj; Newton, Chad; Kim, John; Konkol, Sam; Pugashetti, Janelle; Liu, Gabrielle; Goobie, Gillian; Adegunsoye, Ayodeji; Ma, Shwu-Fan; Bornstein, Drew; Murray, Susan; Wain, Louise; Saini, Gauri; Stewart, Iain; Johnson, Simon; Jenkins, Gisli; Strek, Mary; Linderholm, Angela; Chen, Ching-Hsien; Fahy, William; Zemans, Rachel; Moore, Bethany; Khanna, Dinesh; Ryerson, Christopher; Flaherty, Kevin; Suresh, Madathilparambil; Hoffmann-Vold, Anna-Maria; Maher, Toby; Garcia, Christine; Wolters, Paul; Martinez, Fernando; Noth, Imre; Smith, Jennifer A

Local photocrosslinking of native tissue matrix regulates lung epithelial cell mechanosensing and function.

局部光交联天然组织基质可调节肺上皮细胞的力学感知和功能。

Ahmed Donia W, Tan Matthew L, Liu Yuchen, Gabbard Jackson, Gao Esther, Roy Avinava, Hu Michael M, Midekssa Firaol S, Stevens Miriam, Wuchu Fulei, Nenwani Minal, Xia Jingyi, Abraham Adam, Nagrath Deepak, Han Lin, Zemans Rachel L, Baker Brendon M, Loebel Claudia

Soluble CD13 is a potential mediator of neutrophil-induced thrombogenic inflammation in SARS-CoV-2 infection

可溶性CD13是SARS-CoV-2感染中中性粒细胞诱导的血栓形成性炎症的潜在介质

Pei-Suen Tsou ,Ramadan A Ali ,Chenyang Lu ,Gautam Sule ,Carmelo Carmona-Rivera ,Serena Lucotti ,Yuzo Ikari ,Qi Wu ,Phillip L Campbell ,Mikel Gurrea-Rubio ,Kohei Maeda ,Sharon E Fox ,William D Brodie ,Megan N Mattichak ,Caroline Foster ,Ajay Tambralli ,Srilakshmi Yalavarthi ,M Asif Amin ,Katarina Kmetova ,Bruna Mazetto Fonseca ,Emily Chong ,Yu Zuo ,Michael D Maile ,Luisa Imberti ,Arnaldo Caruso ,Francesca Caccuri ,Virginia Quaresima ,Alessandra Sottini ,Douglas B Kuhns ,Danielle Fink ,Riccardo Castagnoli ,Ottavia M Delmonte ,Heather Kenney ,Yu Zhang ,Mary Magliocco ,Helen Su ,Luigi Notarangelo ,Rachel L Zemans ,Yang Mao-Draayer ,Irina R Matei ,Mirella Salvatore ,David Lyden ,Yogendra Kanthi ,Mariana J Kaplan ,Jason S Knight ,David A Fox

Multi-omic and Single-Cell Approaches for Elucidating Cell Biology and Pathobiology of Lung Disease

利用多组学和单细胞方法阐明肺部疾病的细胞生物学和病理生物学

Sarma, Aartik; Sun, Xin; Sucre, Jennifer; Hong, Jason; Medzikovic, Lejla; Jakubzick, Claudia V; Li, Xin; Zemans, Rachel L; Singer, Benjamin D

Long-term immune reprogramming of classical monocytes with altered ontogeny mediates enhanced lung injury in sepsis survivors.

经典单核细胞的长期免疫重编程及其个体发育的改变,导致脓毒症幸存者肺损伤加剧

Denstaedt Scott J, McBean Breanna, Boyle Alan P, Arenberg Brett C, Mack Matthias, Moore Bethany B, Newstead Michael W, Deng Yanmei, Nesvizhskii Alexey I, Singer Benjamin H, Cano Jennifer, Prescott Hallie C, Goodridge Helen S, Zemans Rachel L

Biomarkers Unveil Insights into Pathology of Transitional Epithelial States in Pulmonary Fibrosis

生物标志物揭示肺纤维化中过渡上皮状态的病理学见解

Ting, Christopher; Konopka, Kristine; Benedeck, Rachel E; Riches, David W H; Redente, Elizabeth F; Oldham, Justin M; Zemans, Rachel L

Proteomic Biomarkers of Survival in Idiopathic Pulmonary Fibrosis

特发性肺纤维化生存的蛋白质组学生物标志物

Oldham, Justin M; Huang, Yong; Bose, Swaraj; Ma, Shwu-Fan; Kim, John S; Schwab, Alexandra; Ting, Christopher; Mou, Kaniz; Lee, Cathryn T; Adegunsoye, Ayodeji; Ghodrati, Sahand; Pugashetti, Janelle Vu; Nazemi, Nazanin; Strek, Mary E; Linderholm, Angela L; Chen, Ching-Hsien; Murray, Susan; Zemans, Rachel L; Flaherty, Kevin R; Martinez, Fernando J; Noth, Imre

Molecular Endotypes of Idiopathic Pulmonary Fibrosis: A Latent Class Analysis of Two Multicenter Observational Cohorts

特发性肺纤维化的分子内型:两项多中心观察性队列研究的潜在类别分析

Maddali, Manoj V; Moore, Andrew R; Sinha, Pratik; Newton, Chad A; Kim, John S; Adegunsoye, Ayodeji; Ma, Shwu-Fan; Strek, Mary E; Chen, Ching-Hsien; Linderholm, Angela L; Zemans, Rachel L; Moore, Bethany B; Wolters, Paul J; Martinez, Fernando J; Rogers, Angela J; Raj, Rishi; Noth, Imre; Oldham, Justin M

MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution

MAPK 磷酸酶 1 抑制肺肌成纤维细胞内的 p38α 对自发性纤维化消退至关重要

Sean M Fortier, Natalie M Walker, Loka R Penke, Jared D Baas, Qinxue Shen, Jennifer M Speth, Steven K Huang, Rachel L Zemans, Anton M Bennett, Marc Peters-Golden