日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

SIRPα extracellular domain shed from neutrophils by ADAM10 aggravates sepsis via initiating nitric oxide release from erythrocyte

中性粒细胞经ADAM10释放的SIRPα胞外结构域通过启动红细胞释放一氧化氮加剧脓毒症。

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2025.08.019
Liang, Hongwei; Lu, Geng; Bian, Zhen; Qu, Shuang; Shi, Lei; Wang, Jun; Zen, Ke; Liu, Yuan
中性粒细胞
炎症/感染
红细胞
败血症
ADA
细胞生物学
ADAM10
粒细胞
发表日期：2026
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CKAP4 in Extracellular Vesicle-Derived From Podocyte Serves as a Non-Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification.

CKAP4 存在于足细胞衍生的细胞外囊泡中，可作为糖尿病肾病的非侵入性诊断生物标志物，并促进血管钙化。

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.70208
Zhang Heng, Lou Kaibin, Qian Li, Zhang Min, Li Jie, Lv Lizhi, Lu Fang, He Guiyang, Wu Chong, Wu Junxiang, Jia Meng, Bai Yang, Qu Shuang, Liu Meng, Chu Laping, Wang Yangtian, Ding Dafa, Zen Ke, Yuan Yanggang, Liang Hongwei
糖尿病
糖尿病肾病
细胞生物学
CKAP4
囊泡
发表日期：2025
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Loss of glomerular aldolase B in diabetic nephropathy promotes renal fibrosis via activating Akt/GSK/β-catenin axis.

糖尿病肾病中肾小球醛缩酶 B 的缺失通过激活 Akt/GSK/β-catenin 轴促进肾纤维化。

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2024.12.027
Liu Minghui, Yang Wenwen, Qu Shuang, Zhao Tingting, Jiang Song, Peng Suming, Zhang Mingchao, Xuan Ji, Liu Zhihong, Zen Ke
糖尿病
糖尿病肾病
代谢
发表日期：2025
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NONO interacts with nuclear PKM2 and directs histone H3 phosphorylation to promote triple-negative breast cancer metastasis.

NONO 与核 PKM2 相互作用，并指导组蛋白 H3 磷酸化，从而促进三阴性乳腺癌转移

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03343-5
Li Qixiang, Ci Hongfei, Zhao Pengpeng, Yang Dongjun, Zou Yi, Chen Panhai, Wu Dongliang, Shangguan Wenbing, Li Wenyang, Meng Xingjun, Xing Mengying, Chen Yuzhong, Zhang Ming, Chen Bing, Kong Lingdong, Zen Ke, Huang David C S, Jiang Zhi-Wei, Zhao Quan
肿瘤
乳腺癌
磷酸化
发表日期：2025
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B cell-derived exosomal tRNA-Pro-TGG served as a non-invasive biomarker and mediator of inflammation in progressive IgA nephropathy

B细胞来源的外泌体tRNA-Pro-TGG可作为进行性IgA肾病中的非侵入性生物标志物和炎症介质。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1679290
Zhang, Heng; He, Guiyang; He, Juanjuan; Li, Changyang; Lv, Lizhi; Jia, Meng; Lu, Fang; Liang, Jun; Wu, Junxiang; Zhou, Xinhao; Jia, Shaochang; Zen, Ke; Yuan, Yanggang; Liang, Hongwei
IgA
B细胞
外泌体
炎症
炎症/感染
细胞生物学
免疫/内分泌
发表日期：2025
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Urinary extracellular vesicle RNAs as novel biomarkers for diagnosis and prognosis of lupus nephritis.

尿液细胞外囊泡RNA作为狼疮性肾炎诊断和预后的新型生物标志物。

期刊:Clinical Kidney Journal
影响因子:4.6
doi:10.1093/ckj/sfaf295
Zhang Heng, Zheng Xuexue, Huang Saisai, Qian Li, Wu Junxiang, Shi Zhongtian, Jia Meng, Bai Yang, Jiang Longwei, Jia Shaochang, Zen Ke, Yuan Yanggang, Liang Jun, Liang Hongwei
肾炎
细胞生物学
囊泡
发表日期：2025
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EBF2 Links KMT2D-Mediated H3K4me1 to Suppress Pancreatic Cancer Progression via Upregulating KLLN

EBF2通过上调KLLN，将KMT2D介导的H3K4me1与胰腺癌进展联系起来，从而抑制胰腺癌进展。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202302037
Yao, Bing; Xing, Mengying; Meng, Shixin; Li, Shang; Zhou, Jingwan; Zhang, Ming; Yang, Chen; Qu, Shuang; Jin, Yucui; Yuan, Hongyan; Zen, Ke; Ma, Changyan
KMT2D
胰腺癌
肿瘤
肿瘤免疫
发表日期：2024
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A novel method to purify small RNAs from human tissues for methylation analysis by LC-MS/MS

一种从人体组织中纯化小RNA并利用LC-MS/MS进行甲基化分析的新方法

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2022.949181
Yang, Rong; Li, Jianfeng; Wu, Yifan; Jiang, Xinli; Qu, Shuang; Wang, Qiang; Liang, Hongwei; Zen, Ke
表观遗传
多发性硬化症
发表日期：2022
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PKM2 controls the degranulation of secondary and tertiary granules in neutrophils by phosphorylating SNAP-23

PKM2通过磷酸化SNAP-23来控制中性粒细胞中二级和三级颗粒的脱颗粒。

期刊:Cellular & Molecular Immunology
影响因子:19.8
doi:10.1038/s41423-021-00718-4
Sun, Xinlei; Wang, Dong; Wang, Yan; Ye, Lei; Shi, Fujie; Qu, Shuang; Liang, Hongwei; Zen, Ke
信号转导
磷酸化
细胞生物学
中性粒细胞
粒细胞
发表日期：2021
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Correction to: PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

更正：PRMT1介导的H4R3me2a通过增强EGFR信号传导募集SMARCA4以促进结直肠癌进展

期刊:Genome Medicine
影响因子:11.2
doi:10.1186/s13073-021-00966-z
Yao, Bing; Gui, Tao; Zeng, Xiangwei; Deng, Yexuan; Wang, Zhi; Wang, Ying; Yang, Dongjun; Li, Qixiang; Xu, Peipei; Hu, Ruifeng; Li, Xinyu; Chen, Bing; Wang, Jin; Zen, Ke; Li, Haitao; Davis, Melissa J; Herold, Marco J; Pan, Hua-Feng; Jiang, Zhi-Wei; Huang, David C S; Liu, Ming; Ju, Junyi; Zhao, Quan
肿瘤
肠癌
肿瘤免疫
信号转导
EGF
PRMT1
EGFR
ARC
发表日期：2021
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