Whole-gene CRISPR/cas9 library screen revealed targeting STAT6 increased the sensitivity of liver cancer to celecoxib via inhibiting arachidonic acid shunting.
全基因 CRISPR/Cas9 文库筛选显示，靶向 STAT6 可通过抑制花生四烯酸分流来提高肝癌对塞来昔布的敏感性
期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-025-02374-x
Hu Chujiao, Zeng Zhirui, Bao Xin, Li Dahuan, Tai Huading, Zeng Haohao, Luo Cheng, Tang Lei, Chen Tengxiang, Zuo Shi
