KAT2A-driven succinylation of SRSF11 enforces spliceosome-mediated RAD52 splicing to promote homologous recombination and radioresistance in hepatocellular carcinoma
KAT2A驱动的SRSF11琥珀酰化增强剪接体介导的RAD52剪接，从而促进肝细胞癌中的同源重组和放射抗性。
期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02458-7
Wu, Jun; Yuan, Jingsheng; Liu, Zijian; Zhou, Yongjie; Zhang, Bo; Xu, Yahong; Zeng, Qiwen; Wu, Zhenru; Kong, Lingxiang; Wang, Jiaguo; Zhang, Bohan; Yang, Jian; Lv, Tao; Shi, Yujun; Yang, Jiayin
肿瘤
琥珀酰化
肿瘤免疫
KAT2A
SRSF1
RAD52
细胞生物学
