In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP.
体外鉴定出奥利多宁杂合物作为潜在的抗三阴性乳腺癌药物，可通过调节 p21、γH2AX 和裂解的 PARP 诱导细胞周期停滞和凋亡
期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d4md00580e
Ning Jinhua, Zhan Nini, Wu Zhanpan, Li Yuzhe, Zhang Die, Shi Yadian, Zhou Yingxun, Chen Chuan-Huizi, Jin Wenbin
