日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Amiodarone irrecoverably impairs the function of human ether-a-go-go-related gene potassium channels

胺碘酮会不可逆转地损害人类醚-a-go-go相关基因钾通道的功能。

期刊:Molecular Pharmacology
影响因子:3
doi:10.1016/j.molpha.2025.100094
Gelman, Illia; Li, Wentao; Guo, Jun; Bogart-Cherry, Reese; Tomei, Nicole; Sharma, Neelakshi; Pan, Angelia; Yang, Tonghua; Baranchuk, Adrian; El-Diasty, Mohammad; Zhang, Shetuan
发表日期：2026
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Rescue of expression and function of long QT syndrome-causing mutant hERG channels by enhancing channel stability in the plasma membrane

通过增强质膜中通道的稳定性来恢复导致长QT综合征的突变型hERG通道的表达和功能

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2024.107526
Davis, Jordan; Cornwell, James D; Campagna, Noah; Guo, Jun; Li, Wentao; Yang, Tonghua; Wang, Tingzhong; Zhang, Shetuan
ERG
发表日期：2024
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Clemizole hydrochloride blocks cardiac potassium currents stably expressed in HEK 293 cells

盐酸克米唑可阻断在HEK 293细胞中稳定表达的心脏钾电流。

期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/bph.13679
Jie, Ling-Jun; Wu, Wei-Yin; Li, Gang; Xiao, Guo-Sheng; Zhang, Shetuan; Li, Gui-Rong; Wang, Yan
细胞生物学
发表日期：2017
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The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11

血清和糖皮质激素诱导激酶SGK1和SGK3通过泛素连接酶Nedd4-2和GTP酶Rab11调节hERG通道的表达。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M113.453670
Lamothe, Shawn M; Zhang, Shetuan
SGK1
信号转导
ERG
Rab11
SGK3
免疫/内分泌
发表日期：2013
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Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2.

人类醚-a-go-go相关基因（hERG）通道的细胞表面表达受caveolin-3蛋白通过泛素连接酶Nedd4-2调控

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.389643
Guo Jun, Wang Tingzhong, Li Xian, Shallow Heidi, Yang Tonghua, Li Wentao, Xu Jianmin, Fridman Michael D, Yang Xiaolong, Zhang Shetuan
细胞生物学
Human
发表日期：2012
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Interaction between the cardiac rapidly (IKr) and slowly (IKs) activating delayed rectifier potassium channels revealed by low K+-induced hERG endocytic degradation

低钾诱导的hERG内吞降解揭示了心脏快速激活延迟整流钾通道（IKr）和慢速激活延迟整流钾通道（IKs）之间的相互作用

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M111.253351
Guo, Jun; Wang, Tingzhong; Yang, Tonghua; Xu, Jianmin; Li, Wentao; Fridman, Michael D; Fisher, John T; Zhang, Shetuan
ERG
发表日期：2011
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The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions

低钾条件下单泛素化在人醚-a-go-go相关基因（hERG）通道内吞降解中的作用

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.198408
Sun, Tao; Guo, Jun; Shallow, Heidi; Yang, Tonghua; Xu, Jianmin; Li, Wentao; Hanson, Christian; Wu, James G; Li, Xian; Massaeli, Hamid; Zhang, Shetuan
ERG
泛素化
表观遗传
发表日期：2011
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The calmodulin inhibitor N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide directly blocks human ether à-go-go-related gene potassium channels stably expressed in human embryonic kidney 293 cells

钙调蛋白抑制剂N-(6-氨基己基)-5-氯-1-萘磺酰胺可直接阻断在人胚肾293细胞中稳定表达的人醚à-go-go相关基因钾通道。

期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/j.1476-5381.2010.00916.x
Zhang, Xiao-Hua; Jin, Man-Wen; Sun, Hai-Ying; Zhang, Shetuan; Li, Gui-Rong
细胞生物学
发表日期：2010
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Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels

Caveolin参与低钾诱导的细胞表面人醚-a-go-go相关基因（hERG）通道的内吞降解

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.124909
Massaeli, Hamid; Sun, Tao; Li, Xian; Shallow, Heidi; Wu, Jimmy; Xu, Jianmin; Li, Wentao; Hanson, Christian; Guo, Jun; Zhang, Shetuan
ERG
细胞生物学
发表日期：2010
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Na+ permeation and block of hERG potassium channels

Na+ 渗透和 hERG 钾通道阻滞

期刊:Journal of General Physiology
影响因子:2.9
doi:10.1085/jgp.200609500
Gang, Hongying; Zhang, Shetuan
ERG
发表日期：2006
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