Triple targeting of STING, TGF-β, and PD-L1 boosts CXCL16-CXCR6 signaling for potent antitumor response.
靶向 STING、TGF-β 和 PD-L1 的三重靶向作用可增强 CXCL16-CXCR6 信号传导，从而产生强大的抗肿瘤反应。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69456-3
Yi Ming, Li Tianye, Gu Yinhui, Niu Mengke, Xue Dixuan, Hu Shengtao, Wu Yuze, Zhao Bin, Zhang Di, Ma Yingkang, Zhang Minjun, Zhang Jing, Yan Yongxiang, Zhou Pengfei, Zhang Xiaojun, Zhou Zhuxian, Chu Qian, Wu Kongming, Dai Zhijun
肿瘤
肿瘤免疫
信号转导
CXCL1
PD-L1
CXCL16
STING
