UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma
UHRF1/UBE2L6/UBR4介导的泛素化调控EZH2的丰度，从而影响黑色素瘤中黑色素细胞的分化表型。
期刊:Oncogene
影响因子:7.3
doi:10.1038/s41388-023-02631-8
Kuser-Abali, Gamze; Zhang, Youfang; Szeto, Pacman; Zhao, Peinan; Masoumi-Moghaddam, Samar; Fedele, Clare G; Leece, Isobel; Huang, Cheng; Cheung, Jen G; Ameratunga, Malaka; Noguchi, Fumihito; Andrews, Miles C; Wong, Nicholas C; Schittenhelm, Ralf B; Shackleton, Mark
黑色素瘤
表观遗传
信号转导
泛素化
UHRF1
EZH2
细胞生物学
