日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Decoding the Role of H19 in Cholestatic Liver Injury Using snRNA-seq, Spatial Transcriptomics, and Machine Learning-Based Disease Prediction

利用snRNA测序、空间转录组学和基于机器学习的疾病预测来解码H19在胆汁淤积性肝损伤中的作用

期刊:
影响因子:
doi:10.21203/rs.3.rs-8339668/v1
Way, Grayson Welch; Jiang, Xixian; Lu, Hongkun; Wu, Nan; Zhao, Derrick; Tai, Yun-Ling; Bayatpour, Sareh; Wang, Xuan; Zhou, Huiping
肝损伤
毒理研究
发表日期：2026
文献求助 收藏

Transcriptomics, lipidomics, and single-nucleus RNA sequencing integration: exploring sphingolipids in MASH-HCC progression

转录组学、脂质组学和单核RNA测序整合：探索MASH-HCC进展中的鞘脂

期刊:Cell and Bioscience
影响因子:6.2
doi:10.1186/s13578-025-01362-5
Zeng, Jing; Way, Grayson; Wu, Nan; Jiang, Xixian; Tai, Yun-Ling; Zhao, Derrick; Su, Lianyong; Yan, Qianhua; Wang, Xuan; Gurley, Emily C; Hylemon, Phillip B; Aseem, Sayed Obaidullah; Sanyal, Arun J; Fan, Jiangao; Zhou, Huiping
发表日期：2025
文献求助 收藏

Intestinal mucosal mitochondrial oxidative phosphorylation worsens with cirrhosis progression and is ameliorated with fecal microbiota transplantation

随着肝硬化的进展，肠黏膜线粒体氧化磷酸化作用恶化，而粪便微生物移植可以改善这一状况。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.186649
Zeng, Jing; Zhao, Derrick; Way, Grayson; Fagan, Andrew; Fuchs, Michael; Puri, Puneet; Davis, Brian C; Wang, Xuan; Gurley, Emily C; Hylemon, Phillip B; Fan, Jian-Gao; Sikaroodi, Masoumeh; Gillevet, Patrick M; Zhou, Huiping; Bajaj, Jasmohan S
信号转导
微生物学
线粒体
肝硬化
磷酸化
发表日期：2025
文献求助 收藏

Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes.

Aramchol 可减轻胆道纤维化小鼠模型中的纤维化，并阻断胆管细胞中 TGFβ 诱导的纤维炎症介质

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000748
Aseem Sayed Obaidullah, Wang Jing, Kalaiger Maleeha F, Way Grayson, Zhao Derrick, Tai Yunling, Gurley Emily, Zeng Jing, Wang Xuan, Cowart Lauren Ashley, Huebert Robert C, Hylemon Phillip B, Jalan-Sakrikar Nidhi, Sanyal Arun J, Zhou Huiping
细胞生物学
Mouse
炎症
发表日期：2025
文献求助 收藏

Sphingosine kinase 2 (SphK2) depletion alters redox metabolism and enhances inflammation in a diet-induced MASH mouse model

鞘氨醇激酶 2 (SphK2) 的缺失会改变氧化还原代谢，并加剧饮食诱导的 MASH 小鼠模型中的炎症反应。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000570
Jackson, Kaitlyn G; Zhao, Derrick; Su, Lianyong; Lipp, Marissa K; Toler, Cameron; Idowu, Michael; Yan, Qianhua; Wang, Xuan; Gurley, Emily; Wu, Nan; Puri, Puneet; Chen, Qun; Lesnefsky, Edward J; Dupree, Jeffrey L; Hylemon, Phillip B; Zhou, Huiping
炎症/感染
信号转导
炎症
代谢
发表日期：2024
文献求助 收藏

Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes

Aramchol 可减轻小鼠胆道纤维化模型中的纤维化，并阻断胆管细胞中 TGFβ 诱导的纤维炎症介质。

期刊:
影响因子:
doi:10.1101/2024.11.06.621880
Aseem, Sayed Obaidullah; Way, Grayson; Wang, Jing; Zhao, Derrick; Tai, Yunling; Gurley, Emily; Zeng, Jing; Wang, Xuan; Hylemon, Phillip B; Huebert, Robert C; Sanyal, Arun J; Zhou, Huiping
细胞生物学
炎症/感染
炎症
TGFβ
发表日期：2024
文献求助 收藏

Bile Acid Receptors and the Gut-Liver Axis in Nonalcoholic Fatty Liver Disease

胆汁酸受体与非酒精性脂肪肝疾病中的肠-肝轴

期刊:Cells
影响因子:5.2
doi:10.3390/cells10112806
Xue, Rui; Su, Lianyong; Lai, Shengyi; Wang, Yanyan; Zhao, Derrick; Fan, Jiangao; Chen, Weidong; Hylemon, Phillip B; Zhou, Huiping
信号转导
脂肪肝
代谢
发表日期：2021
文献求助 收藏

Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions

胆管细胞来源的外泌体lncRNA H19在胆汁淤积条件下促进巨噬细胞活化和肝脏炎症

期刊:Cells
影响因子:5.2
doi:10.3390/cells9010190
Li, Xiaojiaoyang; Liu, Runping; Wang, Yanyan; Zhu, Weiwei; Zhao, Derrick; Wang, Xuan; Yang, Hang; Gurley, Emily C; Chen, Weidong; Hylemon, Phillip B; Zhou, Huiping
巨噬细胞
外泌体
炎症
炎症/感染
巨噬细胞
Immunology/Inflammation
lncRNA
细胞生物学
肝炎
免疫/内分泌
发表日期：2020
文献求助 收藏

Cholangiocyte-Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis

胆管细胞来源的外泌体长链非编码RNA H19促进肝星状细胞活化和胆汁淤积性肝纤维化

期刊:Hepatology
影响因子:15.8
doi:10.1002/hep.30662
Liu, Runping; Li, Xiaojiaoyang; Zhu, Weiwei; Wang, Yanyan; Zhao, Derrick; Wang, Xuan; Gurley, Emily C; Liang, Guang; Chen, Weidong; Lai, Guanhua; Pandak, William M; Robert Lippman, H; Bajaj, Jasmohan S; Hylemon, Phillip B; Zhou, Huiping
外泌体
细胞生物学
发表日期：2019
文献求助 收藏

Effect of Increasing Age on Brain Dysfunction in Cirrhosis

年龄增长对肝硬化患者脑功能障碍的影响

期刊:Hepatology Communications
影响因子:4.6
doi:10.1002/hep4.1286
Liu, Runping; Ahluwalia, Vishwadeep; Kang, Jason D; Ghosh, Siddhartha S; Zhou, Huiping; Li, Yunzhou; Zhao, Derrick; Gurley, Emily; Li, Xiaojiaoyang; White, Melanie B; Fagan, Andrew; Lippman, H Robert; Wade, James B; Hylemon, Phillip B; Bajaj, Jasmohan S
肝硬化
神经科学
发表日期：2019
文献求助 收藏