日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An engineered antibody-lectin conjugate targeting the HIV glycan shield protects humanized mice against HIV challenge

一种靶向HIV聚糖屏障的工程化抗体-凝集素偶联物可保护人源化小鼠免受HIV攻击。

Kumariya, Rashmi; Sun, Jiadong; Lusvarghi, Sabrina; O'Dell, Sijy; Zhao, Gengxiang; Doria-Rose, Nicole A; Bewley, Carole A

Evaluation of AlphaFold modeling for elucidation of nanobody-peptide epitope interactions.

AlphaFold 模型在阐明纳米抗体-肽表位相互作用中的应用评价

Sachdev Shivani, Roy Swarnali, Saha Shubhra J, Zhao Gengxiang, Kumariya Rashmi, Creemer Brendan A, Yin Rui, Pierce Brian G, Bewley Carole A, Cheloha Ross W

Evaluation of Alphafold modeling for elucidation of nanobody-peptide epitope interactions

Alphafold模型在阐明纳米抗体-肽表位相互作用中的应用评价

Sachdev, Shivani; Roy, Swarnali; Saha, Shubhra; Zhao, Gengxiang; Kumariya, Rashmi; Creemer, Brendan A; Yin, Rui; Pierce, Brian G; Bewley, Carole A; Cheloha, Ross W

Structural Basis for a Dual Function ATP Grasp Ligase That Installs Single and Bicyclic ω-Ester Macrocycles in a New Multicore RiPP Natural Product

一种双功能ATP结合酶的结构基础,该酶可将单环和双环ω-酯大环引入新型多核RiPP天然产物中。

Zhao, Gengxiang; Kosek, Dalibor; Liu, Hong-Bing; Ohlemacher, Shannon I; Blackburne, Brittney; Nikolskaya, Anastasia; Makarova, Kira S; Sun, Jiadong; Barry Iii, Clifton E; Koonin, Eugene V; Dyda, Fred; Bewley, Carole A

Vertirhodins A-F, C-Linked Pyrrolidine-Iminosugar-Containing Pyranonaphthoquinones from Streptomyces sp. B15-008

Vertirhodins AF,来自链霉菌属 B15-008 的含 C-连接吡咯烷亚氨基糖的吡喃萘醌

Sun, Jiadong; Zhao, Gengxiang; O'Connor, Robert D; Davison, Jack R; Bewley, Carole A

Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle

利用牛津纳米孔Flongle平台对土壤放线菌进行多重低覆盖度全基因组测序,实现基因组引导的天然产物发现

Rajwani, Rahim; Ohlemacher, Shannon I; Zhao, Gengxiang; Liu, Hong-Bing; Bewley, Carole A

Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium Lentzea sp. GA3-008

Lentzeacins AE,来自富含 BGC 的土壤细菌 Lentzea sp 的新型细菌衍生的 2,5- 和 2,6-二取代吡嗪。 GA3-008

Liu, Hong-Bing; Davison, Jack R; Rajwani, Rahim; Zhao, Gengxiang; Ohlemacher, Shannon I; O'Connor, Robert D; Bewley, Carole A

Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis

9-脱氯金霉素A的合成使得研究能够揭示枯草芽孢杆菌中细菌细胞壁生物合成抑制表型。

Fullenkamp, Christopher R; Hsu, Yen-Pang; Quardokus, Ellen M; Zhao, Gengxiang; Bewley, Carole A; VanNieuwenhze, Michael; Sulikowski, Gary A

Precision medicine in rare disease: Mechanisms of disparate effects of N-carbamyl-l-glutamate on mutant CPS1 enzymes

罕见病精准医疗:N-氨甲酰-L-谷氨酸对突变型CPS1酶的不同作用机制

Shi, Dashuang; Zhao, Gengxiang; Ah Mew, Nicholas; Tuchman, Mendel

Structures of the N-acetyltransferase domain of Xylella fastidiosa N-acetyl-L-glutamate synthase/kinase with and without a His tag bound to N-acetyl-L-glutamate

快速木霉N-乙酰-L-谷氨酸合成酶/激酶的N-乙酰转移酶结构域与H标签结合和未结合的N-乙酰-L-谷氨酸的结构

Zhao, Gengxiang; Jin, Zhongmin; Allewell, Norma M; Tuchman, Mendel; Shi, Dashuang