DRP1 downregulation impairs mitophagy, driving mitochondrial ROS and SASP production in rheumatoid arthritis CD4(+)PD-1(+)T cells
DRP1下调会损害线粒体自噬，从而导致类风湿性关节炎CD4(+)PD-1(+)T细胞中线粒体活性氧（ROS）和SASP的产生。
期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103818
Bai, Ziran; Ren, Jinyi; Liu, Jiaqing; Zhang, Cheng; Huang, Huina; Zhao, Xiangge; Chen, Xianmei; Wei, Jing; Qi, Jingjing; Yang, Siwen; Li, Weiping; Tang, Yawei; Wang, Guan; Li, Xia
T细胞
细胞生物学
PD-1
DRP1
T细胞
线粒体
关节炎
自噬
CD4
免疫/内分泌
