Targeting TET3 suppresses group 3 medulloblastoma stemness and progression via impairing hypomethylation of Otx2 super-enhancer.
靶向 TET3 可抑制 3 组髓母细胞瘤干细胞特性和进展，其机制是通过损害 Otx2 超级增强子的低甲基化。
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102474
Chen Xuan, Wang Ziwei, Song Yan, Su Yu, Zhao Yahui, Li Jiankang, Wang Wei, Zhang Jiao, Daniels Craig, Wu Xiaochong, Saulnier Olivier, Wang Yanan, Liu Fei, Deng Kaiwen, Han Dongming, Liu Zijia, Li Meiyu, Hendrikse Liam D, Rasnitsyn Alexandra, Wang Evan Y, Wang Dongyang, Feng Zhaoyang, Li Yanong, Zhao Zitong, Yuan Hongyu, Sun Youliang, Jiang Yifei, Shi Yanfeng, Yang Tao, Qi Xueling, Hou Yong, Li Chunde, Liu Yong-Qiang, Tian Yu, Li Shuaicheng, Qiu Xiaoguang, Taylor Michael D, Li Guo Liang, Jiang Tao, Liu Hailong
