日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dual-Locking the SARS-CoV-2 Spike Trimer: An Amphipathic Molecular "Bolt" Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition.

双重锁定 SARS-CoV-2 刺突蛋白三聚体：两亲性分子“螺栓”稳定保守的可药物界面以抑制冠状病毒

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202417534
Li Shiliang, Ye Fang, Zheng Yucheng, Wang Jie, Peng Haoran, Zhu Lili, Chen Lili, Yu Tao, Ge Huan, He Jiaqi, Zhang Binghao, Wu Jiayun, Zhang Zhiyi, Jiang Liangliang, Chen Geng, Zhao Ping, Lan Ke, Zhao Zhenjiang, Qian Xuhong, Xu Ke, Du Yang, Li Honglin
炎症/感染
新冠
药物研究
发表日期：2025
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Tamsulosin ameliorates bone loss by inhibiting the release of Cl(-) through wedging into an allosteric site of TMEM16A

坦索罗辛通过楔入TMEM16A的变构位点抑制Cl(-)的释放，从而改善骨质流失。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2407493121
Li, Shiliang; Sun, Weijia; Li, Shuang; Zhu, Lili; Guo, Shuai; He, Jiaqi; Li, Yuheng; Tian, Chaoquan; Zhao, Zhenjiang; Yu, Tao; Li, Jianwei; Zhang, Yiqing; Hai, Youlong; Wang, Jiawen; Zheng, Yongjun; Wang, Rui; Hu, Xiaoyong; Ling, Shukuan; Li, Honglin; Li, Yingxian
发表日期：2025
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Exploring the macrocyclic chemical space for heuristic drug design with deep learning models

利用深度学习模型探索大环化学空间，以进行启发式药物设计

期刊:Communications Chemistry
影响因子:6.2
doi:10.1038/s42004-025-01686-w
Hu, Feng; Jia, Xiaotong; Liao, Wenjie; Chen, Ziqi; Bi, Hongjie; Ge, Huan; Liu, Dandan; Zhang, Rongrong; Hu, Yuting; Mei, Wenyi; Zhao, Zhenjiang; Zhang, Kai; Zhu, Lili; Diao, Yanyan; Li, Honglin
发表日期：2025
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End-to-side anastomosis and autologous pulmonary artery patch for aortic coarctation and hypoplastic aortic arch

采用端侧吻合术和自体肺动脉补片治疗主动脉缩窄和主动脉弓发育不良

期刊:Journal of Thoracic Disease
影响因子:1.9
doi:10.21037/jtd-24-1635
Zhao, Zhenjiang; Wu, Chun; Dai, Jiangtao; Lu, Siwei; He, Ling; Tian, Jie; Jin, Xin; Pan, Zhengxia
发育与干细胞
发表日期：2025
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Binding Free Energy Calculation Based on the Fragment Molecular Orbital Method and Its Application in Designing Novel SHP-2 Allosteric Inhibitors

基于片段分子轨道法的结合自由能计算及其在新型SHP-2变构抑制剂设计中的应用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25010671
Yuan, Zhen; Chen, Xingyu; Fan, Sisi; Chang, Longfeng; Chu, Linna; Zhang, Ying; Wang, Jie; Li, Shuang; Xie, Jinxin; Hu, Jianguo; Miao, Runyu; Zhu, Lili; Zhao, Zhenjiang; Li, Honglin; Li, Shiliang
SHP-2
发表日期：2024
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Risk factors for recurrence after surgical repair of coarctation of the aorta in children: a single-center experience based on 51 children

儿童主动脉缩窄手术修复术后复发的危险因素：基于51例儿童的单中心经验

期刊:Frontiers in Cardiovascular Medicine
影响因子:2.9
doi:10.3389/fcvm.2023.1144755
Zhao, Zhenjiang; Pan, Zhengxia; Wu, Chun; Tian, Jie; Qin, Jinjie; Zhang, Yulin; Jin, Xin
发表日期：2023
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Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2

更正：新型高效靶向DHODH的抑制剂是广谱抗病毒药物，可对抗包括新出现的冠状病毒SARS-CoV-2在内的多种RNA病毒。

期刊:Protein & Cell
影响因子:12.8
doi:10.1007/s13238-020-00801-y
Xiong, Rui; Zhang, Leike; Li, Shiliang; Sun, Yuan; Ding, Minyi; Wang, Yong; Zhao, Yongliang; Wu, Yan; Shang, Weijuan; Jiang, Xiaming; Shan, Jiwei; Shen, Zihao; Tong, Yi; Xu, Liuxin; Chen, Yu; Liu, Yingle; Zou, Gang; Lavillette, Dimitri; Zhao, Zhenjiang; Wang, Rui; Zhu, Lili; Xiao, Gengfu; Lan, Ke; Li, Honglin; Xu, Ke
微生物学
DHODH
SARS-CoV-2
发表日期：2022
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3(2H)-pyridazinone derivatives: a new scaffold for novel plant activators

3(2H)-哒嗪酮衍生物：新型植物活化剂的新骨架

期刊:RSC Advances
影响因子:4.6
doi:10.1039/c9ra06892a
Shi, Qinjie; Shi, Yanxia; Chang, Kang; Chen, Jianqin; Zhao, Zhenjiang; Zhu, Weiping; Xu, Yufang; Li, BaoJu; Qian, Xuhong
发表日期：2019
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Synthesis, Design, and Structure⁻Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

嘧啶酮衍生物作为新型选择性疟原虫二氢乳清酸脱氢酶抑制剂的合成、设计及构效关系研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules23061254
Xu, Le; Li, Wenjie; Diao, Yanyan; Sun, Hongxia; Li, Honglin; Zhu, Lili; Zhou, Hongchang; Zhao, Zhenjiang
发表日期：2018
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Discovery and biological evaluation of N5-substituted 6,7-dioxo-6,7-dihydropteridine derivatives as potent Bruton's tyrosine kinase inhibitors

发现并生物学评价N5取代的6,7-二氧代-6,7-二氢蝶啶衍生物作为强效布鲁顿酪氨酸激酶抑制剂

期刊:Medchemcomm
影响因子:
doi:10.1039/c8md00019k
Chen, Haiyang; Song, Peiran; Diao, Yanyan; Hao, Yongjia; Dou, Dou; Wang, Wanqi; Fang, Xiaoyu; Wang, Yanling; Zhao, Zhenjiang; Ding, Jian; Li, Honglin; Xie, Hua; Xu, Yufang
信号转导
发表日期：2018
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