Zheng Kewei相关文献与解析，生知库 | 链接生命科学的每一步

Cao Heming, Huang Xiawei, Jiang Xiaobing, Deng Jingrong, Wang Jiahui, Wu Chengfang, Hu Minhuang, Zeng Bei, Hu Zhihao, Pan Huimin, Yang Yuxia, Zheng Kewei, Shen Rui, Zhang Mingqing, Liu Bo

信号转导

YAP

Hippo

发表日期：2026

文献求助收藏

Toll signaling controls stem cell proliferation in intestinal regeneration and tumorigenesis

Toll信号通路控制肠道再生和肿瘤发生过程中干细胞的增殖

期刊:EMBO Reports

影响因子:6.2

doi:10.1038/s44319-026-00693-9

Peng, Guofan; Yang, Shichao; Zhang, Yuexia; Zhao, Yu; Huang, Xiaoyun; Yi, Shengen; Gu, Lei; Zhu, Ganqian; Zheng, Kewei; Zhou, Huijun; Han, Kang; Zhou, Jun

Pyridine-bis(benzimidazole) induces DNA damage at G-quadruplex loci and promotes synthetic lethality with DNA repair inhibition.

吡啶双(苯并咪唑)可诱导 G-四链体位点的 DNA 损伤，并通过抑制 DNA 修复促进合成致死

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf543

Yan Jiangyu, Bu Lingli, Wang Yingsha, Yao Haojun, Li Guorui, Zheng Kewei, Huang Jing

信号转导

发表日期：2025

文献求助收藏

RNA G-quadruplex (rG4) exacerbates cellular senescence by mediating ribosome pausing

RNA G-四链体（rG4）通过介导核糖体暂停加剧细胞衰老

期刊:Protein & Cell

影响因子:12.8

doi:10.1093/procel/pwaf047

Zhou, Haoxian; Wu, Shu; Li, Bin; Zhang, Rongjinlei; Zou, Ying; Cao, Mibu; Xu, Anhua; Zheng, Kewei; Zhou, Qinghua; Wang, Jia; Zheng, Jinping; Yang, Jianhua; Ge, Yuanlong; Lin, Zhanyi; Ju, Zhenyu

Therapeutic management of PI3KÎ± inhibitor-induced hyperglycemia with a novel glucokinase activator: Advancing the Frontier of PI3KÎ± inhibitor therapy.

利用新型葡萄糖激酶激活剂治疗PI3Kα抑制剂引起的血糖升高：推进PI3Kα抑制剂治疗的前沿

期刊:Molecular Metabolism

影响因子:6.6

doi:10.1016/j.molmet.2025.102151

Jin Guanqin, Liu Shihuang, Zheng Kewei, Cheng Xiaobo, Chai Ranran, Ye Wei, Wei Wei, Li Yongguo, Huang Ai, Li Guiling, Yi Huan, Kang Yu

Single-cell RNA sequencing reveals the intra-tumoral heterogeneity and immune microenvironment of small cell carcinoma of the ovary, hypercalcemic type.

单细胞 RNA 测序揭示了卵巢小细胞癌（高钙血症型）的肿瘤内异质性和免疫微环境

期刊:Journal of Ovarian Research

影响因子:4.2

doi:10.1186/s13048-025-01649-8

Gao Yi, Zheng Kewei, Tan Haowen, Kang Mingyi, Lu Bingjian, Chen Ling, Xu Jing, Lu Chong, Chai Ranran, Xu Congjian, Kang Yu

SNX10 Is Involved in Ovarian Cancer Cell Metastasis by Repolarizing Tumor-Associated Macrophages Through mTOR1/Lysosomes Pathway.

SNX10 通过 mTOR1/溶酶体通路使肿瘤相关巨噬细胞重新极化，从而参与卵巢癌细胞转移

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines13051021

Chai Ranran, Zheng Kewei, Xu Ting, Wang Hui, Cheng Xiaobo, Lu Chong, Kang Yu

Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma

靶向PI3K/mTOR：透明细胞卵巢癌的潜在治疗策略

期刊:Cancer Chemotherapy and Pharmacology

影响因子:2.3

doi:10.1007/s00280-024-04748-3

Zheng, Kewei; Jin, Guanqin; Cao, Rui; Gao, Yi; Xu, Jing; Chai, Ranran; Kang, Yu

Rhizoma Drynariae-derived nanovesicles reverse osteoporosis by potentiating osteogenic differentiation of human bone marrow mesenchymal stem cells via targeting ER α signaling

骨碎补衍生的纳米囊泡通过靶向 ER α 信号增强人类骨髓间充质干细胞的成骨分化来逆转骨质疏松症

期刊:Acta Pharmaceutica Sinica B

影响因子:14.7

doi:10.1016/j.apsb.2024.02.005

Qing Zhao, Junjie Feng, Fubin Liu, Qianxin Liang, Manlin Xie, Jiaming Dong, Yanfang Zou, Jiali Ye, Guilong Liu, Yue Cao, Zhaodi Guo, Hongzhi Qiao, Lei Zheng, Kewei Zhao

Schizophrenia and type 2 diabetes risk: a systematic review and meta-analysis

精神分裂症与2型糖尿病风险：系统评价和荟萃分析

期刊:Frontiers in Endocrinology

影响因子:4.6

doi:10.3389/fendo.2024.1395771

Dong, Kai; Wang, Shenghai; Qu, Chunhui; Zheng, Kewei; Sun, Ping

The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signaling.

WNK-OXSR1渗透压感知通路通过Hippo-YAP信号介导肠道再生。

Toll signaling controls stem cell proliferation in intestinal regeneration and tumorigenesis

Toll信号通路控制肠道再生和肿瘤发生过程中干细胞的增殖

Pyridine-bis(benzimidazole) induces DNA damage at G-quadruplex loci and promotes synthetic lethality with DNA repair inhibition.

吡啶双(苯并咪唑)可诱导 G-四链体位点的 DNA 损伤，并通过抑制 DNA 修复促进合成致死

RNA G-quadruplex (rG4) exacerbates cellular senescence by mediating ribosome pausing

RNA G-四链体（rG4）通过介导核糖体暂停加剧细胞衰老

Therapeutic management of PI3KÎ± inhibitor-induced hyperglycemia with a novel glucokinase activator: Advancing the Frontier of PI3KÎ± inhibitor therapy.

利用新型葡萄糖激酶激活剂治疗PI3Kα抑制剂引起的血糖升高：推进PI3Kα抑制剂治疗的前沿

Single-cell RNA sequencing reveals the intra-tumoral heterogeneity and immune microenvironment of small cell carcinoma of the ovary, hypercalcemic type.

单细胞 RNA 测序揭示了卵巢小细胞癌（高钙血症型）的肿瘤内异质性和免疫微环境

SNX10 Is Involved in Ovarian Cancer Cell Metastasis by Repolarizing Tumor-Associated Macrophages Through mTOR1/Lysosomes Pathway.

SNX10 通过 mTOR1/溶酶体通路使肿瘤相关巨噬细胞重新极化，从而参与卵巢癌细胞转移

Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma

靶向PI3K/mTOR：透明细胞卵巢癌的潜在治疗策略

Rhizoma Drynariae-derived nanovesicles reverse osteoporosis by potentiating osteogenic differentiation of human bone marrow mesenchymal stem cells via targeting ER α signaling

骨碎补衍生的纳米囊泡通过靶向 ER α 信号增强人类骨髓间充质干细胞的成骨分化来逆转骨质疏松症

Schizophrenia and type 2 diabetes risk: a systematic review and meta-analysis

精神分裂症与2型糖尿病风险：系统评价和荟萃分析