Zhong Xiaolin相关文献与解析，生知库 | 链接生命科学的每一步

Deficiency of extracellular vesicles miR-32 from bone marrow mesenchymal stem cells alleviates vascular calcification in type 2 diabetes by inhibiting endothelial ferroptosis

骨髓间充质干细胞来源的细胞外囊泡 miR-32 缺乏可通过抑制内皮细胞铁死亡来减轻 2 型糖尿病血管钙化。

Lin, Zhengjie; Li, Anqi; Zheng, Jie; Luo, Kun; Liang, Fei; Liu, Shiyan; Liang, Zhengfeng; Liu, Wei; Tang, Jian; Zhong, Xiaolin; Liu, Jianghua

囊泡

Gonadotropin-releasing hormone alleviates chronic pain-related depression in male mice by rebalancing the anterior cingulate cortex excitatory-inhibitory processes via the protein kinase C/Erb-B2 receptor tyrosine kinase 4 pathway

促性腺激素释放激素通过蛋白激酶C/Erb-B2受体酪氨酸激酶4通路重新平衡前扣带回皮层的兴奋性-抑制性过程，从而缓解雄性小鼠的慢性疼痛相关抑郁症。

期刊:Brain Communications

影响因子:4.5

doi:10.1093/braincomms/fcag138

Huang, Yanmei; Chen, Yunfeng; Liu, Xueqin; Xu, Yang; Chen, Ling; Cao, Wenyu; Zhong, Xiaolin

Multi-omics analysis reveals that CAPG positive macrophages are key immunosuppressive drivers and prognostic determinants in the ferroptosis landscape of hepatocellular carcinoma

多组学分析表明，CAPG阳性巨噬细胞是肝细胞癌铁死亡过程中关键的免疫抑制驱动因素和预后决定因素。

期刊:Discover Oncology

影响因子:2.9

doi:10.1007/s12672-026-04649-2

Yin, Xisheng; Li, Yantong; Zheng, Shi; Pan, Chunhui; Tian, Zihan; Zhong, Xiaolin

Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair

局部应用脂质体药物缓释剂可通过抑制炎症和促进软骨修复来增强类风湿性关节炎的治疗效果。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-025-03110-w

Zhang, Zongquan; Wang, Guan; Zhang, Zhuo; Liang, Xiaoya; Wang, Guoshuang; Xu, Maochang; Yang, Xi; Zhong, Xiaolin; Li, Chunhong; Zhou, Meiling

TSPAN4(+) fibroblasts coordinate metastatic niche assembly through migrasome-driven metabolic reprogramming and stromal-immune crosstalk in pancreatic adenocarcinoma

在胰腺腺癌中，TSPAN4(+)成纤维细胞通过迁移体驱动的代谢重编程和基质-免疫串扰协调转移微环境的组装。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1594879

Hu, Qingwen; Chen, Jiali; Liu, Yang; Chen, Haiqing; Lai, Haotian; Jiang, Lai; Zhou, Xuancheng; Zhang, Shengke; Huang, Jinbang; Chi, Hao; Li, Bo; Zhong, Xiaolin

Mechanisms and therapeutic strategies to reveal and overcome T-cell dysfunction in gastric cancer: translation from basic research to clinical application

揭示和克服胃癌中T细胞功能障碍的机制和治疗策略：从基础研究到临床应用的转化

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1681539

Luo, Huanyu; Wu, Jianxi; Yan, Yalan; Xu, Danqi; Zhang, Jieying; Zhou, Xuancheng; Yang, Guanhu; Zhong, Xiaolin

Transcriptional responses in different mouse models of septic liver injury differ from those in patients with septic liver injury.

不同小鼠脓毒症肝损伤模型中的转录反应与脓毒症肝损伤患者的转录反应不同

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1556392

Yan Qin, Fan Wei, He Xinsen, Zheng Shi, Zhong Xiaolin

Leonurine Attenuates CCl(4)-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway.

益母草碱通过 Hippo-YAP 通路减轻 CCl(4) 诱导的小鼠肝纤维化

期刊:Drug Design Development and Therapy

影响因子:5.1

doi:10.2147/DDDT.S518793

Wang Pengru, Bai Junjie, Ye Mingxin, Huang Zhiwei, Chen Jiatong, Sun Lei, Zhong Xiaolin, Zheng Yang, Ma Tingting, Fu Wenguang, Du Yichao

Ursolic acid drug-drug nanocrystals ameliorate cholestatic liver injury via inhibiting oxidative stress and regulating bile acid metabolism

熊果酸药物纳米晶体通过抑制氧化应激和调节胆汁酸代谢来改善胆汁淤积性肝损伤。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1586141

Hu, Manhang; Hua, Xiaolu; Xiong, Wei; Zheng, Enhui; Yang, Xingyue; Lu, Yu; He, Bing; Zhong, Xiaolin; Jiang, Zongzhe; Zhang, Qingbi; Liu, Yan

Novel bidirectional traction technique for tension-regulated large defect closure: a case report

一种新型双向牵引技术用于张力调节型大缺损闭合：病例报告

Deficiency of extracellular vesicles miR-32 from bone marrow mesenchymal stem cells alleviates vascular calcification in type 2 diabetes by inhibiting endothelial ferroptosis

骨髓间充质干细胞来源的细胞外囊泡 miR-32 缺乏可通过抑制内皮细胞铁死亡来减轻 2 型糖尿病血管钙化。

Gonadotropin-releasing hormone alleviates chronic pain-related depression in male mice by rebalancing the anterior cingulate cortex excitatory-inhibitory processes via the protein kinase C/Erb-B2 receptor tyrosine kinase 4 pathway

促性腺激素释放激素通过蛋白激酶C/Erb-B2受体酪氨酸激酶4通路重新平衡前扣带回皮层的兴奋性-抑制性过程，从而缓解雄性小鼠的慢性疼痛相关抑郁症。

Multi-omics analysis reveals that CAPG positive macrophages are key immunosuppressive drivers and prognostic determinants in the ferroptosis landscape of hepatocellular carcinoma

多组学分析表明，CAPG阳性巨噬细胞是肝细胞癌铁死亡过程中关键的免疫抑制驱动因素和预后决定因素。

Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair

局部应用脂质体药物缓释剂可通过抑制炎症和促进软骨修复来增强类风湿性关节炎的治疗效果。

TSPAN4(+) fibroblasts coordinate metastatic niche assembly through migrasome-driven metabolic reprogramming and stromal-immune crosstalk in pancreatic adenocarcinoma

在胰腺腺癌中，TSPAN4(+)成纤维细胞通过迁移体驱动的代谢重编程和基质-免疫串扰协调转移微环境的组装。

Mechanisms and therapeutic strategies to reveal and overcome T-cell dysfunction in gastric cancer: translation from basic research to clinical application

揭示和克服胃癌中T细胞功能障碍的机制和治疗策略：从基础研究到临床应用的转化

Transcriptional responses in different mouse models of septic liver injury differ from those in patients with septic liver injury.

不同小鼠脓毒症肝损伤模型中的转录反应与脓毒症肝损伤患者的转录反应不同

Leonurine Attenuates CCl(4)-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway.

益母草碱通过 Hippo-YAP 通路减轻 CCl(4) 诱导的小鼠肝纤维化

Ursolic acid drug-drug nanocrystals ameliorate cholestatic liver injury via inhibiting oxidative stress and regulating bile acid metabolism

熊果酸药物纳米晶体通过抑制氧化应激和调节胆汁酸代谢来改善胆汁淤积性肝损伤。