Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK.

在人类 SH-SY5Y 神经母细胞瘤细胞中沉默 ACAT1 基因可抑制环氧合酶 2 (COX2) 的表达，并因蛋白激酶 C (PKC) 和 ERK 的激活而降低 β-淀粉样蛋白诱导的毒性