Gingipains disrupt bone homeostasis via dual regulation of osteogenesis and osteoclastogenesis through exosomal miR-146a-5p/TRAF6 signaling.
姜蛋白酶通过外泌体 miR-146a-5p/TRAF6 信号传导对成骨和破骨细胞生成进行双重调节,从而破坏骨骼稳态
期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.8
doi:10.3389/fcimb.2025.1614126
Dong Jiachen, Liao Yue, Sun Mengjun, Chen Huiwen, Zhou Kecong, Zhang Huanyu, Zhou Wei, Song Zhongchen