The deubiquitination-PARylation positive feedback loop of the USP10-PARP1 axis promotes DNA damage repair and affects therapeutic efficacy of PARP1 inhibitor.
USP10-PARP1轴的去泛素化-PARylation正反馈环路促进DNA损伤修复，并影响PARP1抑制剂的治疗效果
期刊:Oncogene
影响因子:7.3
doi:10.1038/s41388-025-03428-7
Liu Jingwei, Zhang Siyi, Cao Liangzi, Zhang Naijin, Guo Qiqiang, Zou Yu, Yang Ruohan, Dong Shiyuan, Zheng Lixia, Xiao Yutong, Wang Yubang, Lu Songming, Jiang Pengcheng, Zhou Keshen, Chen Shu, Chen Di, Li Hao, Zhang Ying, Sheng Ren, Xing Chengzhong, Song Xiaoyu, Wang Zhenning, Cao Liu
