Targeting senescent EGR1(+) B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma.
靶向衰老的 EGR1(+) B 细胞可增强食管鳞状细胞癌的免疫治疗效果。
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102532
Zhou Pingjing, Zhang Yuchen, Zhang Hongyu, Zhao Pengyuan, Guo Yifan, Zhao Guangyin, Chu Yiwei, Ge Di, Liu Ronghua, Gu Jie
肿瘤
T细胞
EGR1
肿瘤免疫
衰老
细胞生物学
免疫/内分泌