日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dual targeted gene delivery strategy mediated by GalNAc-modified lipid nanoparticles enhances liver regeneration through specific knockdown of MKK4

利用 GalNAc 修饰的脂质纳米颗粒介导的双靶向基因递送策略，通过特异性敲低 MKK4 来增强肝脏再生。

期刊:Materials Today Bio
影响因子:10.2
doi:10.1016/j.mtbio.2026.103059
Zhai, Xiao-Pei; Xing, Jie-Hua; Hou, Li-Shuang; Zhang, Tang-Rui; He, Wei; Gan, Li-She; Zhou, Si-Yuan; Zhang, Bang-Le
发表日期：2026
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Downregulation of PGAM2 alleviates angiotensin II-induced cardiac hypertrophy by destabilizing HSP90 and inactivating the mTOR/IKKα signaling pathway

PGAM2 的下调通过破坏 HSP90 的稳定性并抑制 mTOR/IKKα 信号通路，从而减轻血管紧张素 II 诱导的心脏肥大。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.102251
Li, Ying; Li, Wen-Jing; Du, Jia-Min; Wu, Hui-Hui; Zhou, Si-Yuan; Li, Min; Li, Yue-Yan; Wang, Shu-Ya; Wang, Hui-Yun; Zheng, Yan; Zhang, Qun-Ye; Li, Li-Ming; Meng, Fan-Liang; Su, Guo-Hai
mTOR
发表日期：2025
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CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.

CDX1 通过调节 LAPTM4B 来减轻自噬通量受损，从而改善尼古丁诱导的心脏成纤维细胞活化和心肌细胞肥大

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-94160-5
Li Yue-Yan, Meng Fan-Liang, Zhou Si-Yuan, Du Jia-Min, Li Wen-Jing, Liu Qi-Yun, Wu Lei, Zhao Meng-Meng, Jin Yi, Zhang Qun-Ye, Li Ying, Su Guo-Hai
细胞生物学
心肌炎
自噬
发表日期：2025
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Predictive value of pretreatment peripheral blood N/CD4 and N/CD8 ratios for the efficacy of radiotherapy for esophageal cancer

治疗前外周血N/CD4和N/CD8比值对食管癌放疗疗效的预测价值

期刊:Radiology and Oncology
影响因子:2.2
doi:10.2478/raon-2025-0015
Jiang, Yu-Rong; Su, Yu-Ting; Hu, Jing; Ding, Yan; Wang, Lu; Wang, Zi-Yu; Sheng, Wan-Ying; Fan, Yi-Xu; Chu, Liang-Mei; Yang, Yu-Fei; Wen, Yi; Han, Miao; Zhou, Si-Yuan; Dai, Chun-Hua; Wang, Xu
肿瘤
T细胞
肿瘤免疫
CD8
食管癌
CD4
发表日期：2025
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Metformin normalizes mitochondrial function to delay astrocyte senescence in a mouse model of Parkinson's disease through Mfn2-cGAS signaling

二甲双胍通过 Mfn2-cGAS 信号传导使帕金森病小鼠模型中的线粒体功能正常化，从而延缓星形胶质细胞衰老

期刊:Journal of Neuroinflammation
影响因子:9.3
doi:10.1186/s12974-024-03072-0
Min Wang #, Tian Tian #, Hong Zhou #, Si-Yuan Jiang, Ying-Ying Jiao, Zhu Zhu, Jiang Xia, Jian-Hua Ma, Ren-Hong Du
信号转导
神经
帕金森
胶质细胞
FCM
IF
IHC-P
WB
Senescence
Human
发表日期：2024
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FLT3+ DC inhibits immune rejection via interaction with Treg in liver transplantation

FLT3+ DC 通过与 Treg 相互作用抑制肝移植中的免疫排斥

期刊:International Immunopharmacology
影响因子:4.8
doi:10.1016/j.intimp.2024.112289
Jin-Ming Zhang, Hao Huang, Xin-Qiang Li, Shi-Peng Li, Liu-Xin Zhou, Si-Yuan Song, Zhi-Jun Zhu
免疫
T细胞
发表日期：2024
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A pilot study of neoadjuvant combination of anti-PD-1 camrelizumab and VEGFR2 inhibitor apatinib for locally advanced resectable oral squamous cell carcinoma

抗 PD-1 卡瑞利珠单抗与 VEGFR2 抑制剂阿帕替尼新辅助联合治疗局部晚期可切除口腔鳞状细胞癌的初步研究

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-33080-8
Wu-Tong Ju, Rong-Hui Xia, Dong-Wang Zhu, Sheng-Jin Dou, Guo-Pei Zhu, Min-Jun Dong, Li-Zhen Wang, Qi Sun, Tong-Chao Zhao, Zhi-Hang Zhou, Si-Yuan Liang, Ying-Ying Huang, Yong Tang, Si-Cheng Wu, Jing Xia, Shi-Qing Chen, Yue-Zong Bai, Jiang Li, Qi Zhu, Lai-Ping Zhong
肿瘤
口腔癌
其它细胞
IHC
发表日期：2022
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Comparison of Effects and Brain-Gut Regulatory Mechanisms of Acupuncture and Flunarizine for Migraine: Study Protocol for a Randomized Controlled Trial

针灸与氟桂利嗪治疗偏头痛的疗效及脑-肠调节机制比较：一项随机对照试验的研究方案

期刊:Evidence-Based Complementary and Alternative Medicine
影响因子:
doi:10.1155/2021/5676718
Wang, Ya-Nan; Sun, Ming-Sheng; Ni, Xi-Xiu; Tian, Tian; Liu, Lu; Li, Xiao; Xu, Tao; Zhou, Si-Yuan; Chen, Jiao; Liang, Fan-Rong; Liu, Ji-Xin; Zhao, Ling
偏头痛
神经科学
发表日期：2021
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Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery

用于siRNA递送的电荷可逆钙磷酸盐脂质杂化纳米颗粒

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.17484
Cai, Rong-Qiao; Liu, Dao-Zhou; Cui, Han; Cheng, Ying; Liu, Miao; Zhang, Bang-Le; Mei, Qi-Bing; Zhou, Si-Yuan
发表日期：2017
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Activity- and development-dependent down-regulation of TARPγ8 and GluA1 in cultured rat hippocampal neurons

培养的大鼠海马神经元中TARPγ8和GluA1的表达下调与活动和发育相关

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/aps.2015.112
Wang, Jian-gang; Wang, Ya-li; Xu, Fang; Zhao, Jing-xi; Zhou, Si-yuan; Yu, Yi; Chazot, Paul L; Wang, Xiao-fang; Lu, Cheng-biao
发育与干细胞
Rat
神经科学
发表日期：2016
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