日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigation of Renal Tissue Deposition of the Calcineurin Inhibitors Voclosporin, Cyclosporine and Tacrolimus Using MALDI-MSI Imaging

利用MALDI-MSI成像技术研究钙调磷酸酶抑制剂沃克洛孢素、环孢素和他克莫司在肾脏组织中的沉积

Zhou, Simon; Rajanayake, Krishani Kumari; He, Miao; Wen, Bo; Lkhagva, Ankhbayar; Yap, Ernie; Sun, Duxin; Cross, Jennifer; Engelke, Kory; Huizinga, Robert B

Voclosporin ameliorates proteinuria in a model of non-inflammatory glomerular disease

Voclosporin可改善非炎症性肾小球疾病模型中的蛋白尿。

Kamigaki, Yu; Dougherty, Julie A; Waller, Amanda P; Wolfgang, Katelyn J; Rehaume, Linda M; Cross, Jennifer L; Zhou, Simon; Biederman, Laura E; Stevenson, Zackary S; Abdelghani, Eman; Kerlin, Bryce A; Smoyer, William E

Evidence of RNA polymerase III recruitment and transcription at protein-coding gene promoters

RNA聚合酶III在蛋白质编码基因启动子处募集和转录的证据

K C Rajendra, Ruiying Cheng, Sihang Zhou, Simon Lizarazo, Duncan Smith, Kevin Van Bortle

Characterizing the exposure-response relationship of idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma

描述idecabtagene vicleucel在复发/难治性多发性骨髓瘤患者中的暴露-反应关系

Connarn, Jamie N; Witjes, Han; van Zutphen-van Geffen, Marielle; de Greef, Rik; Campbell, Timothy B; Hege, Kristen; Zhou, Simon; Lamba, Manisha

A Phase 1, Multicenter, Open-Label Study to Evaluate the Pharmacokinetics of Iberdomide in Subjects with Mild, Moderate, or Severe Hepatic Impairment Compared with Healthy Subjects

一项 1 期、多中心、开放标签研究,旨在评估伊比度胺在轻度、中度或重度肝功能损害受试者与健康受试者中的药代动力学差异。

Cheng, Yiming; Ye, Ying; Gaudy, Allison; Ghosh, Atalanta; Xue, Yongjun; Wang, Alice; Zhou, Simon; Li, Yan

Why 90% of clinical drug development fails and how to improve it?

为什么90%的临床药物研发会失败,以及如何提高成功率?

Sun, Duxin; Gao, Wei; Hu, Hongxiang; Zhou, Simon

Effect of fluconazole on the pharmacokinetics of a single dose of fedratinib in healthy adults

氟康唑对健康成人单次服用fedratinib药代动力学的影响

Chen, Yizhe; Ogasawara, Ken; Wood-Horrall, Rebecca; Thomas, Mark; Thomas, Michael; He, Bing; Liu, Liangang; Xue, Yongjun; Surapaneni, Sekhar; Carayannopoulos, Leonidas N; Zhou, Simon; Palmisano, Maria; Krishna, Gopal

Aiding early clinical drug development by elucidation of the relationship between tumor growth inhibition and survival in relapsed/refractory multiple myeloma patients

通过阐明肿瘤生长抑制与复发/难治性多发性骨髓瘤患者生存率之间的关系,助力早期临床药物研发

Cheng, Yiming; Hong, Kevin; Chen, Nianhang; Yu, Xin; Peluso, Teresa; Zhou, Simon; Li, Yan

Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A

HIV-1 Vpr 与人类核苷酸切除修复蛋白 hHR23A 复合的结构

In-Ja L Byeon #, Guillermo Calero #, Ying Wu, Chang H Byeon, Jinwon Jung, Maria DeLucia, Xiaohong Zhou, Simon Weiss, Jinwoo Ahn, Caili Hao, Jacek Skowronski, Angela M Gronenborn

Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer

可溶性鸟苷酸环化酶信号传导介导进展性小细胞肺癌的依托泊苷耐药性

Maximilian W Schenk ,Sam Humphrey ,A S Md Mukarram Hossain ,Mitchell Revill ,Sarah Pearsall ,Alice Lallo ,Stewart Brown ,Samuel Bratt ,Melanie Galvin ,Tine Descamps ,Cong Zhou ,Simon P Pearce ,Lynsey Priest ,Michelle Greenhalgh ,Anshuman Chaturvedi ,Alastair Kerr ,Fiona Blackhall ,Caroline Dive ,Kristopher K Frese