HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion
HE4通过IFN-γR-JAK-STAT3信号通路驱动髓系细胞中PD-L1的表达，从而促进肿瘤免疫逃逸。
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2026.102691
Zeng, Bo; Zhou, Yingying; Wang, Heping; Shu, Panyin; Pan, Ting; Liu, Fangfang; Li, Yangyang; Yi, Ming; He, Ruirui; Feng, Lingyun; Cui, Zhihui; Huang, Guoling; Du, Yanyun; Li, Xi; Chen, Chuwen; Chu, Qian; Wang, Yuan; Xiao, Xue; Wang, Chenhui
信号转导
STAT3
IFN-γ
免疫/内分泌
细胞生物学
JAK/STAT
PD-L1
肿瘤
肿瘤免疫
