日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modulation of inner junction proteins contributes to axoneme differentiation

内连接蛋白的调节有助于轴丝分化

Zhe Chen, Ming Li, Hao Zhu, Guangshuo Ou

The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure

线粒体调节因子PGC1α受cGMP-PKG信号通路诱导,并介导磷酸二酯酶5抑制剂在心力衰竭中的保护作用。

Zhu, Guangshuo; Ueda, Kazutaka; Hashimoto, Masaki; Zhang, Manling; Sasaki, Masayuki; Kariya, Taro; Sasaki, Hideyuki; Kaludercic, Nina; Lee, Dong-Ik; Bedja, Djahida; Gabrielson, Matthew; Yuan, Yuan; Paolocci, Nazareno; Blanton, Robert M; Karas, Richard H; Mendelsohn, Michael E; O'Rourke, Brian; Kass, David A; Takimoto, Eiki

Chronic Atrial and Ventricular Pacing in the Mouse

小鼠慢性心房和心室起搏

Ståhlberg, Marcus; Nakagawa, Ryo; Bedja, Djahida; Zhu, Guangshuo; Lin, Brian L; Saberi, Amir; Lee, Dong I; Kass, David A

Blood outgrowth endothelial cells overexpressing eNOS mitigate pulmonary hypertension in rats: a unique carrier cell enabling autologous cell-based gene therapy

过表达eNOS的血管外生内皮细胞可缓解大鼠肺动脉高压:一种独特的载体细胞,可实现自体细胞基因治疗

Somani, Arif; Nair, Sethu L; Milbauer, Liming C; Zhu, Guangshuo; Sajja, Suchitra; Solovey, Anna; Chen, Yingjie; Hebbel, Robert P

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.

心肌肌球蛋白结合蛋白 C 中钙蛋白酶靶向位点的消融在缺血再灌注损伤期间具有心脏保护作用

Barefield David Y, McNamara James W, Lynch Thomas L, Kuster Diederik W D, Govindan Suresh, Haar Lauren, Wang Yang, Taylor Erik N, Lorenz John N, Nieman Michelle L, Zhu Guangshuo, Luther Pradeep K, Varró Andras, Dobrev Dobromir, Ai Xun, Janssen Paul M L, Kass David A, Jones Walter Keith, Gilbert Richard J, Sadayappan Sakthivel

Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition

磷酸二酯酶1型抑制剂对心脏功能的急性增强作用

Hashimoto, Toru; Kim, Grace E; Tunin, Richard S; Adesiyun, Tolulope; Hsu, Steven; Nakagawa, Ryo; Zhu, Guangshuo; O'Brien, Jennifer J; Hendrick, Joseph P; Davis, Robert E; Yao, Wei; Beard, David; Hoxie, Helen R; Wennogle, Lawrence P; Lee, Dong I; Kass, David A

S-Nitrosoglutathione Reductase Is Essential for Protecting the Female Heart From Ischemia-Reperfusion Injury

S-亚硝基谷胱甘肽还原酶对于保护女性心脏免受缺血再灌注损伤至关重要

Casin, Kevin M; Fallica, Jonathan; Mackowski, Nathan; Veenema, Ryne J; Chan, Ashley; St Paul, Amanda; Zhu, Guangshuo; Bedja, Djahida; Biswal, Shyam; Kohr, Mark J

Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation

抑制PKG-1α氧化可抑制PDE5抑制剂的抗肥大/抗纤维化作用,但不会抑制sGC刺激作用。

Nakamura, Taishi; Zhu, Guangshuo; Ranek, Mark J; Kokkonen-Simon, Kristen; Zhang, Manling; Kim, Grace E; Tsujita, Kenichi; Kass, David A

Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease

cGMP选择性PDE5抑制剂与PDE9抑制剂在心脏病中对microRNA调控的显著差异

Kokkonen-Simon, Kristen M; Saberi, Amir; Nakamura, Taishi; Ranek, Mark J; Zhu, Guangshuo; Bedja, Djahida; Kuhn, Michaela; Halushka, Marc K; Lee, Dong Ik; Kass, David A

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy

瞬时受体电位通道6调节杜氏肌营养不良症中异常的心脏S-亚硝基化

Chung, Heaseung Sophia; Kim, Grace E; Holewinski, Ronald J; Venkatraman, Vidya; Zhu, Guangshuo; Bedja, Djahida; Kass, David A; Van Eyk, Jennifer E