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Development and validation of a novel analytical method for related substances of resmetirom and identification of new degradation products

开发并验证了一种用于分析雷斯美替隆相关物质的新型分析方法，并鉴定了新的降解产物。

期刊:Frontiers in Chemistry

影响因子:4.2

doi:10.3389/fchem.2026.1795082

Qin, Jisu; Luo, Qunfeng; Wu, Wenyi; Wang, Qin; Cai, Liangliang; Wang, Shuang; Zhu, Yonghong

发表日期：2026

文献求助收藏

Antagonistic Mechanisms of Serratia plymuthica MM Against Phytophthora capsici and Its Growth-Promoting Traits

普氏沙雷氏菌MM对辣椒疫霉的拮抗机制及其促生长特性

期刊:Plants-Basel

影响因子:4.1

doi:10.3390/plants15040586

Wang, Litao; Wang, Fan; Wu, Chenying; Wang, Xu; Li, Yuzhuo; Zheng, Jiaxin; Liu, Yidan; Yang, Xinyi; Liu, Yang; Li, Zhaoyu; Zhang, Zheng; Zhu, Yonghong; Uwaremwe, Constantine; Su, Xu; Tian, Yongqiang

多发性骨髓瘤

发表日期：2026

文献求助收藏

First-in-human phase I study of EMB-02, a bispecific antibody targeting PD-1 and LAG-3 in patients with advanced solid tumors

EMB-02（一种靶向PD-1和LAG-3的双特异性抗体）在晚期实体瘤患者中的首次人体I期研究

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-025-02990-x

Day, Daphne; Ganju, Vinod; Chung, Ki; Si, Lu; Mao, Lili; Aghmesheh, Morteza; Hoyer, Robert; Brewin, Kim; Zeng, Shuqi; Zhang, Mingfei; Lu, Qiaoyang; Jiang, Chengjun; Ren, Fang; Zhu, Yonghong; Guo, Jun

PD-1

发表日期：2025

文献求助收藏

Corrigendum to "The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota" [Volume 10, Issue 2, February 2025, Pages 522-534]

对“溴结构域和末端外蛋白抑制剂阿帕贝他隆通过调节胆固醇积累和调节肠道菌群来改善糖尿病肾损伤”一文的更正[第 10 卷，第 2 期，2025 年 2 月，第 522-534 页]

期刊:Kidney International Reports

影响因子:5.7

doi:10.1016/j.ekir.2025.02.035

Wang, Min; Huang, Zhaohui; Zhu, Yonghong; Li, Xin; Sun, He; Fan, QiuLing

The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota.

溴结构域和末端蛋白抑制剂阿帕贝酮通过调节胆固醇积累和调节肠道菌群来改善糖尿病肾损伤

期刊:Kidney International Reports

影响因子:5.7

doi:10.1016/j.ekir.2024.11.022

Wang Min, Huang Zhaohui, Zhu Yonghong, Li Xin, Sun He, Fan QiuLing

METTL3 alleviates renal tubular mitochondrial dysfunction by regulating the TUG1/PGC-1a axis in an IGF2BP2-dependent manner in diabetic nephropathy

METTL3通过IGF2BP2依赖的方式调节TUG1/PGC-1α轴，从而缓解糖尿病肾病中的肾小管线粒体功能障碍。

期刊:Renal Failure

影响因子:3

doi:10.1080/0886022X.2025.2521455

Chen, Tong; Wang, Juan; Xu, Yanyan; Zhu, Yonghong; Jin, Ying; Fan, Qiuling

Using Pharmacokinetic and Pharmacodynamic Analysis to Optimize the Dosing Regimens of Fanastomig (EMB-02) in Patients With Advanced Solid Tumors

利用药代动力学和药效学分析优化Fanastomig (EMB-02)在晚期实体瘤患者中的给药方案

期刊:Cpt-Pharmacometrics & Systems Pharmacology

影响因子:3

doi:10.1002/psp4.70011

Jiang, Chengjun; Ren, Fang; Zhang, Mingfei; Lu, Qiaoyang; Zeng, Shuqi; Yang, Guang; Zhu, Yonghong

发表日期：2025

文献求助收藏

AtZAT10/STZ1 improves drought tolerance and increases fiber yield in cotton

AtZAT10/STZ1 可提高棉花的耐旱性并增加纤维产量。

期刊:Frontiers in Plant Science

影响因子:4.8

doi:10.3389/fpls.2024.1464828

Qin, Lixia; He, Hehe; Yang, Liqun; Zhang, Huanyang; Li, Jing; Zhu, Yonghong; Xu, Jianguo; Jiao, Gaili; Xiang, Chengbin; Wang, Chuangyun; Wu, Shenjie

发表日期：2024

文献求助收藏

circOMA1 delivered by exosomes regulates DRD2âmediated prolactinoma resistance.

外泌体递送的 circOMA1 调节 DRD2 介导的催乳素瘤耐药性。

Genome-wide identification and characterization of the RPA gene family in maize

玉米RPA基因家族的全基因组鉴定和表征

Development and validation of a novel analytical method for related substances of resmetirom and identification of new degradation products

开发并验证了一种用于分析雷斯美替隆相关物质的新型分析方法，并鉴定了新的降解产物。

Antagonistic Mechanisms of Serratia plymuthica MM Against Phytophthora capsici and Its Growth-Promoting Traits

普氏沙雷氏菌MM对辣椒疫霉的拮抗机制及其促生长特性

First-in-human phase I study of EMB-02, a bispecific antibody targeting PD-1 and LAG-3 in patients with advanced solid tumors

EMB-02（一种靶向PD-1和LAG-3的双特异性抗体）在晚期实体瘤患者中的首次人体I期研究

Corrigendum to "The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota" [Volume 10, Issue 2, February 2025, Pages 522-534]

对“溴结构域和末端外蛋白抑制剂阿帕贝他隆通过调节胆固醇积累和调节肠道菌群来改善糖尿病肾损伤”一文的更正[第 10 卷，第 2 期，2025 年 2 月，第 522-534 页]

The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota.

溴结构域和末端蛋白抑制剂阿帕贝酮通过调节胆固醇积累和调节肠道菌群来改善糖尿病肾损伤

METTL3 alleviates renal tubular mitochondrial dysfunction by regulating the TUG1/PGC-1a axis in an IGF2BP2-dependent manner in diabetic nephropathy

METTL3通过IGF2BP2依赖的方式调节TUG1/PGC-1α轴，从而缓解糖尿病肾病中的肾小管线粒体功能障碍。

Using Pharmacokinetic and Pharmacodynamic Analysis to Optimize the Dosing Regimens of Fanastomig (EMB-02) in Patients With Advanced Solid Tumors

利用药代动力学和药效学分析优化Fanastomig (EMB-02)在晚期实体瘤患者中的给药方案

AtZAT10/STZ1 improves drought tolerance and increases fiber yield in cotton

AtZAT10/STZ1 可提高棉花的耐旱性并增加纤维产量。

circOMA1 delivered by exosomes regulates DRD2âmediated prolactinoma resistance.

外泌体递送的 circOMA1 调节 DRD2 介导的催乳素瘤耐药性。

Genome-wide identification and characterization of the RPA gene family in maize

玉米RPA基因家族的全基因组鉴定和表征

Development and validation of a novel analytical method for related substances of resmetirom and identification of new degradation products

开发并验证了一种用于分析雷斯美替隆相关物质的新型分析方法，并鉴定了新的降解产物。

Antagonistic Mechanisms of Serratia plymuthica MM Against Phytophthora capsici and Its Growth-Promoting Traits

普氏沙雷氏菌MM对辣椒疫霉的拮抗机制及其促生长特性

First-in-human phase I study of EMB-02, a bispecific antibody targeting PD-1 and LAG-3 in patients with advanced solid tumors

EMB-02（一种靶向PD-1和LAG-3的双特异性抗体）在晚期实体瘤患者中的首次人体I期研究

Corrigendum to "The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota" [Volume 10, Issue 2, February 2025, Pages 522-534]

对“溴结构域和末端外蛋白抑制剂阿帕贝他隆通过调节胆固醇积累和调节肠道菌群来改善糖尿病肾损伤”一文的更正[第 10 卷，第 2 期，2025 年 2 月，第 522-534 页]

The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota.

溴结构域和末端蛋白抑制剂阿帕贝酮通过调节胆固醇积累和调节肠道菌群来改善糖尿病肾损伤

METTL3 alleviates renal tubular mitochondrial dysfunction by regulating the TUG1/PGC-1a axis in an IGF2BP2-dependent manner in diabetic nephropathy

METTL3通过IGF2BP2依赖的方式调节TUG1/PGC-1α轴，从而缓解糖尿病肾病中的肾小管线粒体功能障碍。

Using Pharmacokinetic and Pharmacodynamic Analysis to Optimize the Dosing Regimens of Fanastomig (EMB-02) in Patients With Advanced Solid Tumors

利用药代动力学和药效学分析优化Fanastomig (EMB-02)在晚期实体瘤患者中的给药方案

AtZAT10/STZ1 improves drought tolerance and increases fiber yield in cotton

AtZAT10/STZ1 可提高棉花的耐旱性并增加纤维产量。

circOMA1 delivered by exosomes regulates DRD2âmediated prolactinoma resistance.